Document Detail

Impact of a single endometrial injury on assisted reproductive technology outcome: a preliminary observational study.
MedLine Citation:
PMID:  22195334     Owner:  NLM     Status:  In-Process    
OBJECTIVE: To find a more acceptable strategy for our patients to improve endometrial receptivity in assisted reproductive technologies (ART) and to study the impact of a single endometrial sampling performed on day 21 of the spontaneous menstrual cycle.
STUDY DESIGN: In this preliminary study, the possible beneficial effects on ART outcome of a single biopsy performed on the midluteal phase (day 21) of the spontaneous menstrual cycle preceding controlled ovarian stimulation was tested in a group of patients with 3 or more implantation failures.
RESULTS: After endometrial biopsy 45.94% of patients with more than two failed ART cycles obtained clinical pregnancy.
CONCLUSION: Although these preliminary results are encouraging, further investigation is needed to validate the study.
Gian Mario Tiboni; Franca Giampietro; Elisabetta Gabriele; Valeria Di Donato; Gianna Gabriella Impicciatore
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  56     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:    2011 Nov-Dec
Date Detail:
Created Date:  2011-12-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  504-6     Citation Subset:  IM    
Section of Reproductive Sciences, Department of Medicine and Sciences of the Aging, Faculty of Medicine and Surgery, University "G. d'Annunzio," Chieti-Pescara, Italy.
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