Document Detail

Impact of a second transurethral resection on the staging of T1 bladder cancer.
MedLine Citation:
PMID:  12429307     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To evaluate the impact of a second transurethral resection (TUR) on the pathologic stage in a unique patient population with T1 tumors. METHODS: Seventy-one patients with Stage T1 transitional cell carcinoma of the bladder were prospectively enrolled and underwent restaging TUR. Fifteen patients underwent immediate cystectomy and 56 patients were treated endoscopically. The patients who underwent immediate cystectomy were the subjects of this report. RESULTS: Fifteen patients underwent immediate cystectomy. At restaging TUR, 13 patients had persistent T1, 1 patient had Tis, and 1 patient had no residual disease. The pathologic stage at cystectomy revealed the presence of residual disease in 12 of 15 patients, and 3 patients had pT0. Of the 12 patients with residual disease, 3 had residual pT1, 2 had pT1 with pTis, 5 had pTis alone, and 2 had muscle-invasive tumors. Thirteen percent of the patients who underwent immediate cystectomy after restaging TUR had a pathologic stage greater than pT1. CONCLUSIONS: Understaging for T1 disease is negligible after restaging TUR.
Guido Dalbagni; Harry W Herr; Victor E Reuter
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Urology     Volume:  60     ISSN:  1527-9995     ISO Abbreviation:  Urology     Publication Date:  2002 Nov 
Date Detail:
Created Date:  2002-11-13     Completed Date:  2003-01-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0366151     Medline TA:  Urology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  822-4; discussion 824-5     Citation Subset:  IM    
Department of Urology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.
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MeSH Terms
Carcinoma, Transitional Cell / pathology*,  surgery*
Neoplasm Staging
Neoplasm, Residual
Prospective Studies
Urinary Bladder Neoplasms / pathology*,  surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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