Document Detail


Impact of right-ventricular apical pacing on the optimal left-ventricular lead positions measured by phase analysis of SPECT myocardial perfusion imaging.
MedLine Citation:
PMID:  24577949     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE: The use of SPECT phase analysis to optimize left-ventricular (LV) lead positions for cardiac resynchronization therapy (CRT) was performed at baseline, but CRT works as simultaneous right ventricular (RV) and LV pacing. The aim of this study was to assess the impact of RV apical (RVA) pacing on optimal LV lead positions measured by SPECT phase analysis.
METHODS: This study prospectively enrolled 46 patients. Two SPECT myocardial perfusion scans were acquired under sinus rhythm with complete left bundle branch block and RVA pacing, respectively, following a single injection of (99m)Tc-sestamibi. LV dyssynchrony parameters and optimal LV lead positions were measured by the phase analysis technique and then compared between the two scans.
RESULTS: The LV dyssynchrony parameters were significantly larger with RVA pacing than with sinus rhythm (p ~0.01). In 39 of the 46 patients, the optimal LV lead positions were the same between RVA pacing and sinus rhythm (kappa = 0.861). In 6 of the remaining 7 patients, the optimal LV lead positions were along the same radial direction, but RVA pacing shifted the optimal LV lead positions toward the base.
CONCLUSION: The optimal LV lead positions measured by SPECT phase analysis were consistent, no matter whether the SPECT images were acquired under sinus rhythm or RVA pacing. In some patients, RVA pacing shifted the optimal LV lead positions toward the base. This study supports the use of baseline SPECT myocardial perfusion imaging to optimize LV lead positions to increase CRT efficacy.
Authors:
Guang-Uei Hung; Jin-Long Huang; Wan-Yu Lin; Shih-Chung Tsai; Kuo-Yang Wang; Shih-Ann Chen; Michael S Lloyd; Ji Chen
Related Documents :
19853229 - Acute limb ischemia.
2644829 - Altered myocardial states. the stunned and hibernating myocardium.
24310439 - Association between left ventricular regional sympathetic denervation and mechanical dy...
23559909 - Thrombolysis in the age of primary percutaneous coronary intervention: mini-review and ...
3879349 - Localization of post-infarction myocardial ischemia by 201tl emission computed tomography.
2022049 - Right coronary artery disease. pathophysiology, clinical relevance, and methods for rec...
8269499 - Adaptor device for shortening guide catheters to access distal lesions in coronary angi...
16221259 - Clinical results of an advanced svt detection enhancement algorithm.
21459139 - Sophocarpine administration preserves myocardial function from ischemia-reperfusion in ...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-2-28
Journal Detail:
Title:  European journal of nuclear medicine and molecular imaging     Volume:  -     ISSN:  1619-7089     ISO Abbreviation:  Eur. J. Nucl. Med. Mol. Imaging     Publication Date:  2014 Feb 
Date Detail:
Created Date:  2014-2-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101140988     Medline TA:  Eur J Nucl Med Mol Imaging     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  On the Configurational Stability of Chiral, Nonracemic Fluoro- and Iodo-[D1 ]Methyllithiums.
Next Document:  PET/MRI and PET/CT in follow-up of head and neck cancer patients.