Document Detail

Impact of a restriction in the number of embryos transferred on the multiple pregnancy rate.
MedLine Citation:
PMID:  16188374     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To study the impact of the introduction of reimbursement of in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) laboratory costs in Belgium which is linked to an embryo transfer strategy leading to prevention of multiple pregnancies. The impact on the incidence of multiple and twin pregnancy rate as well as on ongoing pregnancy rate in our centre is calculated. STUDY DESIGN: Observational cohort study of all patients in the first year (July 1, 2003-June 30, 2004) since the implementation of the law and comparison of ongoing pregnancy rate and multiple pregnancy rate of our centre with Belgian data. RESULTS: Our results of one year of IVF/ICSI since reimbursement of laboratory costs show a total conception rate of 42.2% with 29.7% ongoing pregnancies beyond 25 weeks amenorrhea. The multiple pregnancy rate was 8.5% including five monozygotic twin pregnancies. These data show an important decline of multiple pregnancy rate when compared to Belgian data (2002) with 24.4% multiple pregnancy rate in the year prior to reimbursement. CONCLUSION: The introduction of reimbursement of IVF/ICSI laboratory costs coupled to a restriction in the number of embryos for transfer has reached the goal of halving the multiple pregnancy rate since its introduction while maintaining an optimal ongoing pregnancy rate.
Diane De Neubourg; Jan Gerris; Eric Van Royen; Kathelijne Mangelschots; Miet Vercruyssen
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Publication Detail:
Type:  Journal Article     Date:  2005-09-26
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  124     ISSN:  0301-2115     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-01-27     Completed Date:  2007-08-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  212-5     Citation Subset:  IM    
Department of Obstetrics-Gynecology-Fertility, Centre for Reproductive Medicine, Middelheim Hospital, Lindendreef 1, 2020 Antwerp, Belgium.
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MeSH Terms
Cohort Studies
Embryo Transfer / economics*
Fertilization in Vitro / economics*
Infertility / therapy
Pregnancy Rate*
Pregnancy, Multiple / statistics & numerical data*
Reimbursement, Incentive* / legislation & jurisprudence
Sperm Injections, Intracytoplasmic / economics

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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