Document Detail


Impact of pulmonary vein isolation on atrial late potentials: association with the recurrence of atrial fibrillation.
MedLine Citation:
PMID:  23059395     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
AIMS: In patients with paroxysmal atrial fibrillation (AF), the P-wave signal-averaged electrocardiogram often demonstrates a low-amplitude potential at the terminal part of filtered P-wave (atrial late potential: A(LP)), which would originate from delayed pulmonary vein (PV) potentials. The aim of this study was to investigate the impact of PV isolation on P-wave morphology, and explore the association between A(LP) and AF recurrence after ablation.METHODS AND RESULTS: We enrolled 88 consecutive paroxysmal AF patients scheduled for ablation. The signal-averaged electrocardiogram was obtained at baseline and 1 day after ablation. An A(LP) was defined as a P-wave duration of ≥130 ms and a root-mean-squared voltage of the terminal 20 ms of ≤2.0 μV. A pre-procedural A(LP) was found in 37 (42%) patients and a post-procedural A(LP) was found in 26 (30%) patients. We completed PV isolation in all patients and followed them for 16 ± 4 months. The AF recurrence rate was 30% (26 patients) and was similar between patients with and without pre-procedural A(LP) (27 vs. 31%, respectively, P = 0.66); however, AF recurrence was significantly higher in patients with than without post-procedural A(LP) (54 vs. 19%, respectively, P = 0.001). In multivariate logistic regression analysis, post-procedural A(LP) was independently associated with AF recurrence (odds ratio = 4.22, 95% confidence interval = 1.52-11.7).CONCLUSION: Pulmonary vein isolation can modify A(LP) in a substantial number of patients with paroxysmal AF. Post-procedural A(LP) is associated with increased risk of future AF recurrence.
Authors:
Masaharu Masuda; Koichi Inoue; Katsuomi Iwakura; Atsunori Okamura; Yuko Toyoshima; Atsushi Doi; Yohei Sotomi; Issei Komuro; Kenshi Fujii
Related Documents :
19887725 - Relationship between lower urinary tract symptoms and urinary atp in patients with beni...
8839665 - Selective liver enzyme induction by carbamazepine and phenytoin in chinese epileptics.
11440745 - Spect imaging of the dopamine transporter with [(123)i]-beta-cit reveals marked decline...
1129905 - Uncomplicated hypospadias and anomalies of upper urinary tract. need for screening?
10367835 - A new temporary catheter (conticath) for the treatment of temporary, reversible, postop...
20514335 - Predicting factors for refractory kawasaki disease.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-11
Journal Detail:
Title:  Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology     Volume:  -     ISSN:  1532-2092     ISO Abbreviation:  Europace     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883649     Medline TA:  Europace     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Cardiovascular Center, Sakurabashi Watanabe Hospital, 2-4-32, Umeda, Kita-ku, Osaka 530-0001, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  THE NOP RECEPTOR INVOLVEMENT IN BOTH WITHDRAWAL- AND CCk-8- INDUCED CONTRACTURE RESPONSES OF GUINEA ...
Next Document:  Everolimus improves experimental autoimmune uveoretinitis.