Document Detail


Impact of prophylactic percutaneous endoscopic gastrostomy on malnutrition and quality of life in patients with head and neck cancer - a randomized study.
MedLine Citation:
PMID:  21374756     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: The purpose of this randomized study was to examine if a prophylactic percutaneous endoscopic gastrostomy (PEG) for enteral nutrition could prevent malnutrition, reduce hospital stay, and improve health-related quality of life (HRQOL). METHODS: One hundred thirty-four patients with advanced head and neck cancer were randomized to either prophylactic PEG (study group) or clinical praxis (control group). Patients' weight, body mass index (BMI), need for hospitalization, and HRQOL were noted at 7 occasions during 2 years. RESULTS: No difference in hospital stay was found. After 6 months, HRQOL was significantly better and the weight loss was significantly less in the study group. The number of malnourished patients were consistently about 10% lower in the study group during the first study year. The study group started to use enteral feeding significantly earlier and for a significantly longer time period (p < .0001). CONCLUSION: Prophylactic PEG was associated with significantly earlier start and longer use of enteral nutrition, fewer malnourished patients over time, and improved HRQOL at 6 months posttreatment start. © 2011 Wiley Periodicals, Inc. Head Neck, 2011.
Authors:
Ewa Silander; Jan Nyman; Mogens Bove; Leif Johansson; Sven Larsson; Eva Hammerlid
Related Documents :
21199286 - Laparoscopic partial nephrectomy for multiple tumours: feasibility and analysis of peri...
9533606 - The time course of post-lumbar puncture headache.
18579806 - Fourteen-year final report of the randomized pdrg-uk trial comparing three initial trea...
19912346 - A double-blind comparison of onabotulinumtoxina (botox) and topiramate (topamax) for th...
12797426 - Overview of medical therapy for gastroesophageal disease.
24418126 - Fixed-time post-cervical artificial insemination in sows receiving porcine luteinising ...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-3
Journal Detail:
Title:  Head & neck     Volume:  -     ISSN:  1097-0347     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8902541     Medline TA:  Head Neck     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2010 Wiley Periodicals, Inc.
Affiliation:
Department of Otorhinolaryngology-Head and Neck Surgery, Sahlgrenska University Hospital, Göteborg Sweden. ewa.silander@vgregion.se.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Morbidity of supraomohyoidal and modified radical neck dissection combined with radiotherapy for hea...
Next Document:  Safety and feasibility of elective minimally invasive video-assisted central neck dissection for thy...