Document Detail


Impact of polycystic ovary syndrome on selected indicators of in vitro fertilization and intracytoplasmic sperm injection treatment success.
MedLine Citation:
PMID:  19368509     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To examine the effect of polycystic ovary syndrome (PCOS), a marker of the metabolic syndrome, on selected indicators of in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) treatment success. METHODS: A retrospective cohort study was conducted using existing data on 69 IVF/ICSI treatment cycles undergone by PCOS women and a caliper-matched sample of 69 IVF/ICSI treatment cycles undergone by non-PCOS women over a 7-year period at a major fertility treatment center. Matching criteria were age and date at IVF/ICSI treatment initiation. Process and outcome measures were used to define successful IVF/ICSI treatment. Statistical significance was determined at an alpha level of 0.05. RESULTS: The total number of oocytes and the number of immature oocytes retrieved in the process of an IVF/ICSI cycle were significantly higher in the context of PCOS. No significant differences were observed among PCOS and non-PCOS groups on various IVF/ICSI cycle outcomes, including high-grade embryo, pregnancy achievement, miscarriage, and live birth status. CONCLUSIONS: Although IVF/ICSI yields more oocytes in the context of PCOS, IVF/ICSI outcomes do not differ significantly by PCOS status. Prospective cohort studies are needed to examine short-term and long-term health effects of PCOS in the context of IVF/ICSI.
Authors:
Hind A Beydoun; Laurel Stadtmauer; Yueqin Zhao; Helena Russell; David O Matson; Sergio Oehninger
Related Documents :
11028929 - Poor quality of sperm as it affects repeated early pregnancy loss.
7819709 - Sperm:oocyte ratios in an in vitro fertilization (ivf) program.
2321109 - Successful pregnancy despite retrograde ejaculation. a case report.
16164429 - Influence of motility and vitality in intracytoplasmic sperm injection with ejaculated ...
16726579 - Comparison of pregnancy rates achieved with frozen semen using two packaging methods.
11868629 - Treatment of sperm with subnormal host scores with chymotrypsin/viable pregnancy after ...
2382159 - Can acetaminophen excess result in maternal and fetal toxicity?
23498309 - Expression of pregnancy-associated glycoprotein family in the epitheliochorial placenta...
16845629 - Cytomegalovirus (cmv)-encoded ul144 (truncated tumor necrosis factor receptor) and outc...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of women's health (2002)     Volume:  18     ISSN:  1931-843X     ISO Abbreviation:  J Womens Health (Larchmt)     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-05-18     Completed Date:  2009-08-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101159262     Medline TA:  J Womens Health (Larchmt)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  717-23     Citation Subset:  IM    
Affiliation:
Graduate Program in Public Health, Eastern Virginia Medical School, 1123 Lewis Hall, 700 W. Olney Road, Norfolk, VA 23501-1980, USA. baydouha@evms.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Cohort Studies
Comorbidity
Embryo Transfer / statistics & numerical data*
Female
Humans
Infertility, Female / epidemiology*,  therapy
Polycystic Ovary Syndrome / epidemiology*,  therapy
Pregnancy
Pregnancy Outcome / epidemiology
Retrospective Studies
Sperm Injections, Intracytoplasmic / statistics & numerical data*
Women's Health
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Consequences of a plant-based diet with low dairy consumption on intake of bone-relevant nutrients.
Next Document:  Adipose stromal cells stimulate angiogenesis via promoting progenitor cell differentiation, secretio...