Document Detail


Impact of ovarian endometrioma on assisted reproduction outcomes.
MedLine Citation:
PMID:  16984764     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effects of ovarian endometrioma on fertility outcomes with IVF and embryo transfer have been causally related to poor outcomes. The objective of this meta-analysis was to evaluate the ovarian reserve and ovarian responsiveness to ovarian stimulation and assisted reproduction outcomes in patients with ovarian endometrioma. The odds for clinical pregnancy were not affected significantly in patients with ovarian endometrioma compared with controls, with an overall odds ratio of 1.07 from three studies [95% CI: (0.63, 1.81), P = 0.79]. The overall pregnancy rate was similar with an estimated odds ratio of 1.17 [95% CI: (0.85, 1.60), P = 0.34]. Decreased ovarian responsiveness to ovarian stimulation in patients with ovarian endometrioma may be due to a reduced number of follicles in these patients compared with controls (P = 0.002). Prospective randomized controlled trials are needed to assess whether surgical treatment versus no surgical treatment improves pregnancy outcomes in patients with ovarian endometrioma undergoing assisted reproduction cycles.
Authors:
Sajal Gupta; Ashok Agarwal; Rishi Agarwal; J Ricardo Loret de Mola
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Publication Detail:
Type:  Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Reproductive biomedicine online     Volume:  13     ISSN:  1472-6483     ISO Abbreviation:  Reprod. Biomed. Online     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-09-20     Completed Date:  2006-12-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101122473     Medline TA:  Reprod Biomed Online     Country:  England    
Other Details:
Languages:  eng     Pagination:  349-60     Citation Subset:  IM    
Affiliation:
Reproductive Research Centre, Glickman Urological Institute and the Department of Obstetrics-Gynecology, Cleveland Clinic Foundation, Cleveland, OH, USA. guptas2@ccf.org
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MeSH Terms
Descriptor/Qualifier:
Endometriosis / complications*,  epidemiology,  therapy,  ultrasonography
Female
Fertilization in Vitro
Humans
Infertility, Female / etiology*
Oocyte Donation
Ovarian Diseases / complications*,  epidemiology,  therapy,  ultrasonography
Ovarian Follicle / pathology
Pregnancy
Pregnancy Outcome
Reproductive Techniques, Assisted*
Selection Bias
Sperm Injections, Intracytoplasmic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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