Document Detail

Impact of organ-specific dose reduction on the image quality of head and neck CT angiography.
MedLine Citation:
PMID:  23300039     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: Organ-specific dose reduction (OSDR) algorithms can reduce radiation on radiosensitive organs up to 59 %. This study evaluates the influence of a new OSDR algorithm on image quality of head and neck computed tomographic angiography (CTA) in clinical routine.
METHODS: Sixty-two consecutive patients (68 ± 13 years) were randomised into two groups and imaged using 128-row multidetector CT. Group A (n = 31) underwent conventional CTA and group B (n = 31) CTA with a novel OSDR algorithm. Subjective and objective image quality were statistically compared. Subjective image quality was rated on a five-point scale. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated with region-of-interest measurements.
RESULTS: The SNR of the common carotid artery and middle cerebral artery was 53.6 ± 22.7 and 43.3 ± 15.3 (group A) versus 54.1 ± 20.5 and 46.2 ± 14.6 (group B). The CNR was 40.0 ± 19.3 and 29.7 ± 12.0 (group A) compared with 40.7 ± 16.8 and 32.9 ± 10.9 (group B), respectively. Subjective image quality was excellent in both groups (mean score 4.4 ± 0.7 versus 4.4 ± 0.6). Differences between the two groups were not significant.
CONCLUSIONS: The novel OSDR algorithm does not compromise image quality of head and neck CTA. Its application can be recommended for CTA in clinical routine to protect the thyroid gland and ocular lenses from unnecessary high radiation.
KEY POINTS: • Organ-specific dose reduction (OSDR) can significantly reduce radiation exposure during CT • OSDR does not compromise image quality of head and neck CTA • OSDR can significantly lower the risk of radiation damage to sensitive organs • OSDR can easily be applied in routine clinical practice.
L Schimmöller; R S Lanzman; P Heusch; S Dietrich; F Miese; J Aissa; T A Heusner; G Antoch; P Kröpil
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial     Date:  2013-01-09
Journal Detail:
Title:  European radiology     Volume:  23     ISSN:  1432-1084     ISO Abbreviation:  Eur Radiol     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-05-17     Completed Date:  2013-12-26     Revised Date:  2014-08-26    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1503-9     Citation Subset:  IM    
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MeSH Terms
Carotid Artery, Common / pathology
Cerebral Angiography / methods*
Contrast Media / pharmacology
Head and Neck Neoplasms / diagnosis*,  pathology*
Middle Aged
Middle Cerebral Artery / pathology
Prospective Studies
Radiation Dosage*
Radiographic Image Interpretation, Computer-Assisted / methods*
Reproducibility of Results
Signal-To-Noise Ratio
Tomography, X-Ray Computed / methods*
Reg. No./Substance:
0/Contrast Media

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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