Document Detail


The impact of network clustering and assortativity on epidemic behaviour.
MedLine Citation:
PMID:  19948179     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Epidemic models have successfully included many aspects of the complex contact structure apparent in real-world populations. However, it is difficult to accommodate variations in the number of contacts, clustering coefficient and assortativity. Investigations of the relationship between these properties and epidemic behaviour have led to inconsistent conclusions and have not accounted for their interrelationship. In this study, simulation is used to estimate the impact of social network structure on the probability of an SIR (susceptible-infective-removed) epidemic occurring and, if it does, the final size. Increases in assortativity and clustering coefficient are associated with smaller epidemics and the impact is cumulative. Derived values of the basic reproduction ratio (R(0)) over networks with the highest property values are more than 20% lower than those derived from simulations with zero values of these network properties.
Authors:
Jennifer Badham; Rob Stocker
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-12-04
Journal Detail:
Title:  Theoretical population biology     Volume:  77     ISSN:  1096-0325     ISO Abbreviation:  Theor Popul Biol     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-01-29     Completed Date:  2010-04-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0256422     Medline TA:  Theor Popul Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  71-5     Citation Subset:  IM    
Copyright Information:
Copyright 2009 Elsevier Inc. All rights reserved.
Affiliation:
School of Engineering and Information Technology, Australian Defence Force Academy, Northcott Drive, Canberra 2600, Australia. research@criticalconnections.com.au
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MeSH Terms
Descriptor/Qualifier:
Algorithms
Australia
Basic Reproduction Number / statistics & numerical data*
Cluster Analysis*
Computer Simulation
Disease Outbreaks / statistics & numerical data*
Disease Transmission, Infectious / statistics & numerical data
Humans
Infection Control / methods,  statistics & numerical data
Influenza, Human / epidemiology,  prevention & control
Markov Chains
Models, Biological
Models, Statistical
Social Support*
World Health

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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