Document Detail


Impact of nasal polyposis on erectile dysfunction.
MedLine Citation:
PMID:  21679515     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Our male patients with chronic rhinosinusitis with nasal polyposis (NP) declare a better sexual function after functional endoscopic sinus surgery (FESS) with polypectomy. This study was planned to conduct the first prospective, controlled trial evaluating the possible relation between erectile dysfunction (ED) and NP by subjective and objective parameters.
METHODS: Thirty-three male patients with NP and thirty randomly selected male control subjects were evaluated. All subjects underwent assessments of nasal endoscopy, rhinomanometry, body mass index (BMI), Epworth Sleepiness Scale, full in-laboratory polysomnograpy and serum levels of glucose, thyroid hormones, lipid profile, and testosterone. ED was evaluated by the erectile function domain of the International Index of Erectile Function (IIEF-EF) subjectively and nocturnal penile tumescence (NPT) objectively. The NP group was reassessed 6 months after FESS.
RESULTS: The mean age, BMI, and laboratory tests of the patients and the control subjects had no significant difference. The well-recognized risk factors for ED were eliminated. Preoperative evaluation of the patients revealed that ED was present in 34 and 24% of the patients by IIEF-EF and NPT, respectively, which was significantly higher than the control group (p = 0.009 and p = 0.018, respectively). There was a significant improvement of ED in the assessment of IIEF-EF and NPT postoperatively (p = 0.014 and p = 0.037, respectively).
CONCLUSION: ED was determined in a high percentage of patients with NP and significantly ameliorated after FESS. NP might present a risk factor in the development of ED.
Authors:
Kivanc Gunhan; Fatih Zeren; Uzdan Uz; Bilal Gumus; Halis Unlu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of rhinology & allergy     Volume:  25     ISSN:  1945-8932     ISO Abbreviation:  Am J Rhinol Allergy     Publication Date:    2011 Mar-Apr
Date Detail:
Created Date:  2011-06-17     Completed Date:  2011-11-01     Revised Date:  2011-11-10    
Medline Journal Info:
Nlm Unique ID:  101490775     Medline TA:  Am J Rhinol Allergy     Country:  United States    
Other Details:
Languages:  eng     Pagination:  112-5     Citation Subset:  IM    
Affiliation:
Department of Otorhinolaryngology, Celal Bayar University, Manisa, Turkey. kivanc.gunhan@bayar.edu.tr
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MeSH Terms
Descriptor/Qualifier:
Adult
Chronic Disease
Disease Progression
Endoscopy*
Erectile Dysfunction / complications,  diagnosis,  pathology,  physiopathology*,  surgery
Follow-Up Studies
Humans
Male
Middle Aged
Nasal Polyps
Penile Erection
Polysomnography
Rhinitis / complications,  diagnosis,  pathology,  physiopathology*,  surgery
Rhinomanometry
Sinusitis / complications,  diagnosis,  physiopathology*,  surgery
Testosterone / blood
Chemical
Reg. No./Substance:
58-22-0/Testosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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