| Impact of myocardial blush on left ventricular remodeling after first anterior myocardial infarction treated successfully with primary coronary intervention. | |
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MedLine Citation:
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PMID: 20803879 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Myocardial blush grade is a useful marker of microvascular reperfusion that may influence left ventricular dilation. OBJECTIVES: To assess the impact of MB grade on LV remodeling in patients undergoing successful primary PCI for first anterior ST elevation myocardial infarction. METHODS: In 26 consecutive patients MB grade was evaluated immediately after primary PCI. Each patient underwent transthoracic echocardiography at 24 hours and 6 months after PCI for evaluation of LV volumes. LV remodeling was defined as an increase in end-diastolic volume by > or = 20%. RESULTS: The presence of myocardial reperfusion (MB 2-3) after primary PCI was associated with a significantly lower rate of remodeling than the absence of myocardial reperfusion (MB 0-1) (17.6% vs. 66.6%, P = 0.012). Accordingly, at 6 months, patients with MB 2-3 had significantly smaller LV end-diastolic volume (94 +/- 21.5 vs. 115.2 +/- 26 ml) compared with patients with MB 0-1. In univariate analysis, only MB (0-1 versus 2-3) was associated with increased risk of LV remodeling (odds ratio 9.3, 95% confidence interval 1.45-60.21, P = 0.019). CONCLUSIONS: Impaired microvascular reperfusion, as assessed by MB 0-1, may be associated with LV remodeling in patients with STEMI treated successfully with primary PCI. |
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Authors:
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Ashraf Hamdan; Ran Kornowski; Eli I Lev; Alexander Sagie; Shmuel Fuchs; David Brosh; Alexander Battler; Abid R Assali |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Israel Medical Association journal : IMAJ Volume: 12 ISSN: 1565-1088 ISO Abbreviation: Isr. Med. Assoc. J. Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-08-31 Completed Date: 2010-09-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100930740 Medline TA: Isr Med Assoc J Country: Israel |
Other Details:
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Languages: eng Pagination: 211-5 Citation Subset: IM |
Affiliation:
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Cardiac Catheterization Laboratories, Department of Cardiology, Rabin Medical Center (Beilinson Campus), Petah Tikva, Israel. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Angioplasty, Transluminal, Percutaneous Coronary
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methods* Coronary Angiography / methods Coronary Circulation* Echocardiography / methods Female Follow-Up Studies Humans Male Middle Aged Myocardial Infarction / therapy* Odds Ratio Ventricular Remodeling* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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