Document Detail


Impact of myocardial blush on left ventricular remodeling after first anterior myocardial infarction treated successfully with primary coronary intervention.
MedLine Citation:
PMID:  20803879     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Myocardial blush grade is a useful marker of microvascular reperfusion that may influence left ventricular dilation. OBJECTIVES: To assess the impact of MB grade on LV remodeling in patients undergoing successful primary PCI for first anterior ST elevation myocardial infarction. METHODS: In 26 consecutive patients MB grade was evaluated immediately after primary PCI. Each patient underwent transthoracic echocardiography at 24 hours and 6 months after PCI for evaluation of LV volumes. LV remodeling was defined as an increase in end-diastolic volume by > or = 20%. RESULTS: The presence of myocardial reperfusion (MB 2-3) after primary PCI was associated with a significantly lower rate of remodeling than the absence of myocardial reperfusion (MB 0-1) (17.6% vs. 66.6%, P = 0.012). Accordingly, at 6 months, patients with MB 2-3 had significantly smaller LV end-diastolic volume (94 +/- 21.5 vs. 115.2 +/- 26 ml) compared with patients with MB 0-1. In univariate analysis, only MB (0-1 versus 2-3) was associated with increased risk of LV remodeling (odds ratio 9.3, 95% confidence interval 1.45-60.21, P = 0.019). CONCLUSIONS: Impaired microvascular reperfusion, as assessed by MB 0-1, may be associated with LV remodeling in patients with STEMI treated successfully with primary PCI.
Authors:
Ashraf Hamdan; Ran Kornowski; Eli I Lev; Alexander Sagie; Shmuel Fuchs; David Brosh; Alexander Battler; Abid R Assali
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Israel Medical Association journal : IMAJ     Volume:  12     ISSN:  1565-1088     ISO Abbreviation:  Isr. Med. Assoc. J.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-08-31     Completed Date:  2010-09-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100930740     Medline TA:  Isr Med Assoc J     Country:  Israel    
Other Details:
Languages:  eng     Pagination:  211-5     Citation Subset:  IM    
Affiliation:
Cardiac Catheterization Laboratories, Department of Cardiology, Rabin Medical Center (Beilinson Campus), Petah Tikva, Israel.
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MeSH Terms
Descriptor/Qualifier:
Angioplasty, Transluminal, Percutaneous Coronary / methods*
Coronary Angiography / methods
Coronary Circulation*
Echocardiography / methods
Female
Follow-Up Studies
Humans
Male
Middle Aged
Myocardial Infarction / therapy*
Odds Ratio
Ventricular Remodeling*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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