| Impact of metabolic syndrome on re-stenosis development: Role of drug-eluting stents. | |
| | |
MedLine Citation:
|
PMID: 22219135 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Metabolic syndrome (MetS) is defined as a cluster of numerous cardiovascular risk factors, which encompasses obesity, dyslipidaemia, insulin resistance and hypertension. Patients with MetS are more prone to developing cardiovascular events than other patients. To date, several approaches such as physical exercise, dietary control and invasive and non-invasive therapeutic interventions for dyslipidaemia, hypertension and insulin resistance have been used to manage MetS. However, there is a progressive elevation in the incidence of fatal and non-fatal cardiovascular events due to the increased prevalence of obesity and diabetes. Percutaneous coronary intervention has emerged over the last few years as an effective revascularisation strategy for those with coronary artery disease, in parallel with the development of effective anti-platelet medications and newer drug-eluting stents. In recent years, considerable research efforts have been undertaken to elucidate the pathophysiology of re-stenosis and develop strategies to prevent re-stenosis following percutaneous transluminal coronary angioplasty and stent implantation. Although the rate of stent re-stenosis and target-lesion revascularisation has been reduced, there is little information in the literature on the outcome of MetS in the pathophysiology of re-stenosis. In this review article, we summarise the recent development and progress on re-stenosis and the role of drug-eluting stents, particularly in MetS. |
| | |
Authors:
|
S N Goyal; S Bharti; B Krishnamurthy; Y Agrawal; S K Ojha; D S Arya |
Related Documents
:
|
3942425 - Correlation of postoperative and two-year follow-up angiography with neurological funct... 22048325 - Current developments in transcatheter aortic valve implantation techniques. 21802315 - Experimental model of large pulmonary embolism employing controlled release of subacute... 19046645 - Surgical therapy of extracranial carotid artery aneurysms: long-term results over a 24-... 21838575 - Chronic hyperhomocysteinemia causes vascular remodelling by instigating vein phenotype ... 1992195 - The management of primary pulmonary hypertension. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-1-4 |
Journal Detail:
|
Title: Diabetes & vascular disease research : official journal of the International Society of Diabetes and Vascular Disease Volume: - ISSN: 1752-8984 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
|
Created Date: 2012-1-5 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101234011 Medline TA: Diab Vasc Dis Res Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Age-Related Decline in DNA Polymerase ? Activity in Rat Brain and Tissues.
Next Document: Genetic predisposition of the severity of joint destruction in rheumatoid arthritis: a population-ba...