| Impact of implant technique following freestyle stentless aortic valve replacement. | |
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MedLine Citation:
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PMID: 12400753 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Stentless aortic bioprostheses have excellent hemodynamics and clinical outcomes. The purpose of the present study was to determine whether implant technique of the Freestyle aortic root bioprosthesis impacts clinical outcomes or hemodynamic performance. METHODS: The long-term multicenter study of the Freestyle stentless aortic bioprosthesis includes 500 consecutive patients implanted using the subcoronary and 162 using the full root technique. Clinical outcomes and echocardiographic hemodynamics were compared through 5 years. RESULTS: There were no differences between groups in time to death, valve-related death, or reoperation. The incidence of operative death was higher in the full root than in the subcoronary group (odds ratio 3.97, p = 0.001). Patients in the subcoronary group were more likely to have New York Heart Association functional class III or IV symptoms at 1 year (1.7% versus 0%, p = 0.04) and 5 years postoperatively (4.4% versus 0%, p = 0.02). Mean gradient was lower (p = 0.0004) and effective orifice area larger (p = 0.04) in the full root group. Left ventricular mass index decreased in both groups. The preponderance of patients in both groups had no or trivial aortic regurgitation through 5 years. CONCLUSIONS: Full root implantation of the Freestyle stentless aortic bioprosthesis was associated with higher operative mortality, but somewhat better hemodynamics, functional class, and freedom from aortic regurgitation. Higher operative mortality argues against the empiric replacement of the ascending aorta in the absence of aortic root pathology. In appropriately selected patients, both implant techniques are viable alternatives for valve implantation. |
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Authors:
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David S Bach; Paul C Cartier; Neal D Kon; Katherine G Johnson; G Michael Deeb; Donald B Doty; |
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Publication Detail:
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Type: Comparative Study; Journal Article; Multicenter Study |
Journal Detail:
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Title: The Annals of thoracic surgery Volume: 74 ISSN: 0003-4975 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 2002 Oct |
Date Detail:
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Created Date: 2002-10-28 Completed Date: 2002-11-26 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: United States |
Other Details:
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Languages: eng Pagination: 1107-13; discussion 1113-4 Citation Subset: AIM; IM |
Affiliation:
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Department of Medicine, Division of Cardiology, University of Michigan, Ann Arbor, USA. dbach@umich.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aortic Valve Aortic Valve Insufficiency / prevention & control Bioprosthesis* Echocardiography Heart Valve Prosthesis Implantation / methods*, mortality Hemodynamics Humans Male Middle Aged Reoperation Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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