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Impact of immediate breast reconstruction on postoperative adjuvant chemotherapy: a single center study.
MedLine Citation:
PMID:  23756827     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Various studies have indicated a worldwide increase in the number of immediate breast reconstruction surgeries. However, breast reconstruction should not delay or prevent postoperative cancer therapeutics such as adjuvant chemotherapy and radiotherapy. In response to these developments, our team researched the impact of immediate breast reconstruction on postoperative adjuvant chemotherapy. METHODS: From April 2006 to March 2011, 116 patients at Saitama Cancer Center underwent postoperative adjuvant chemotherapy following mastectomy with or without immediate breast reconstruction. Fifty patients received postoperative adjuvant chemotherapy following mastectomy with immediate breast reconstruction (IBR group), and 66 patients received the same treatment but without immediate breast reconstruction (non-IBR group). The outcomes were studied retrospectively by chart review. Patients' average age, body mass index, postoperative complication rate, and days to adjuvant chemotherapy were calculated. RESULTS: Mean age and body mass index of patients were 47.0 ± 9.0 years, 22.2 ± 3.0 kg/m(2) and 55.5 ± 10.1 years, 23.0 ± 3.6 kg/m(2) in IBR group and non-IBR group, respectively. Postoperative complication rate was 10.0 % in IBR group and 6.1 % in non-IBR group. Days to adjuvant chemotherapy was 61.0 ± 10.5 days in IBR group and 58.0 ± 12.3 days in non-IBR group. CONCLUSIONS: Although complication rate and days to adjuvant chemotherapy were slightly increased in IBR group, the delay was not critical to the initiation of adjuvant chemotherapy in these patient groups.
Authors:
Atsumori Hamahata; Kazuyuki Kubo; Hiroyuki Takei; Takashi Saitou; Yuji Hayashi; Hiroshi Matsumoto; Shigenori Nagai; Kenichi Inoue; Masafumi Kurosumi; Takashi Yamaki; Hiroyuki Sakurai
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-6-12
Journal Detail:
Title:  Breast cancer (Tokyo, Japan)     Volume:  -     ISSN:  1880-4233     ISO Abbreviation:  Breast Cancer     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-6-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888201     Medline TA:  Breast Cancer     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Division of Plastic and Reconstructive Surgery, Saitama Cancer Center, 818 Komuro, Inamachi, Kitaadachigunn, Saitama, Japan, a.hamahata@gmail.com.
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