Document Detail

Impact of gender on outcome after coronary artery bypass surgery.
MedLine Citation:
PMID:  19643848     Owner:  NLM     Status:  MEDLINE    
Following recent studies concerning the increased risk of coronary artery bypass surgery for women, the impact of sex is still a controversial issue. Between 1996 and 2006, 9,527 men and 3,079 women underwent isolated coronary artery bypass in our institute. To adjust for dissimilarities in preoperative risk profiles, propensity score-based matching was applied. Before adjustment, clinical outcomes in terms of operative mortality, arrhythmias, intensive care unit stay, and maximum creatine kinase-MB levels were significantly different for men and women. After balancing the preoperative characteristics, including height, no significant differences in clinical outcomes were observed. However, there was decreased use of internal mammary artery, less total arterial revascularization, and increasing creatine kinase-MB levels with decreasing height. This study supports the theory that female sex per se does not increase operative risk, but shorter height, which is more common in women, affects the outcome, probably due to technical difficulties in shorter patients with smaller internal mammary arteries and coronary vessels. Thus women may especially benefit from sequential arterial grafting.
Ina C Ennker; Alexander Albert; Detlef Pietrowski; Kerstin Bauer; Juergen Ennker; Ines Florath
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Asian cardiovascular & thoracic annals     Volume:  17     ISSN:  1816-5370     ISO Abbreviation:  Asian Cardiovasc Thorac Ann     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-07-31     Completed Date:  2009-10-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9503417     Medline TA:  Asian Cardiovasc Thorac Ann     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  253-8     Citation Subset:  IM    
Mediclin Heart Institute Lahr/Baden, 77933 Lahr, Germany.
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MeSH Terms
Angina Pectoris / epidemiology
Arrhythmias, Cardiac / epidemiology
Body Height
Carotid Stenosis / epidemiology
Coronary Artery Bypass / mortality*
Creatine Kinase, MB Form / analysis
Diabetes Mellitus / epidemiology
Heart Failure / epidemiology
Hyperlipidemias / epidemiology
Hypertension / epidemiology
Intensive Care Units
Length of Stay / statistics & numerical data
Logistic Models
Mammary Arteries / transplantation
Middle Aged
Nervous System Diseases / epidemiology
Outcome Assessment (Health Care)*
Severity of Illness Index
Sex Factors
Smoking / epidemiology
Stroke Volume
Reg. No./Substance:
EC Kinase, MB Form

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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