Document Detail

Impact of female and male obesity on IVF/ICSI: results of 700,000 ART-cycles in Germany.
MedLine Citation:
PMID:  20540669     Owner:  NLM     Status:  In-Data-Review    
To our knowledge, this is the first analysis in which male and female weights have been combined. The registry dataset covering a 12-year period was analysed for all treatment cycles where an embryo transfer was reported. In all, 706,360 cycles were analysed. Treatments include IVF, ICSI, IVF/ICSI and CPE. The highest success rate in IVF cycles was found in couples, with an obese male partner. In the group of obese women, the pregnancy rate decreased to 27.2%. Similar to IVF treatment, the highest success rate in ICSI cycles was found in couples, where either the male or the female partner was obese. The highest success rate in cycles with a cryopreserved embryo transfer was observed in couples where both partner were obese. The lowest success rate was seen where the female partner was obese. Our data analysis suggests that the combination of an obese male and a normal-weight female is positively related to better implantation rates in IVF as well as ICSI-cycles. This combination is more likely to be found in couples with a higher social status. Therefore, the increased pregnancy rate in this group might as well be related to other lifestyle factors associated with higher social status.
Markus S Kupka; Christian Gnoth; Klaus Buehler; Wolfgang Dahncke; Jan-S Kruessel
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Publication Detail:
Type:  Journal Article     Date:  2010-06-14
Journal Detail:
Title:  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology     Volume:  27     ISSN:  1473-0766     ISO Abbreviation:  Gynecol. Endocrinol.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8807913     Medline TA:  Gynecol Endocrinol     Country:  England    
Other Details:
Languages:  eng     Pagination:  144-9     Citation Subset:  IM    
Department of Reproduction Medicine and Endocrinology, Ludwig Maximilians University Munich, Clinic and Outpatient Clinic for Gynecology and Obstetrics, Munich University Hospital ? City Center, Munich, Germany.
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