| Impact of fatigue on the efficacy of rehabilitation in multiple sclerosis. | |
| | |
MedLine Citation:
|
PMID: 21240518 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Fatigue is considered to be one of the most common and disabling symptoms among individuals with multiple sclerosis (MS). The aim of this study is to investigate if an intensive, short-term inpatient rehabilitation program is able to improve fatigue in MS, and if fatigue is able to negatively influence the clinical and functional outcome of rehabilitation in MS. One-hundred eighty six consecutively recruited MS patients underwent an intensive, short-term inpatient rehabilitation program. Sixty-four of them were selected for this study according to our inclusion criteria and compared to a control group of 22 MS patients who did not follow a rehabilitation program. We measured fatigue symptoms with the Fatigue Severity Scale (FSS) before and after rehabilitation, and classified patients into fatigued (FMS) in the case of an FSS score ≥36 and into non-fatigued MS (NFMS) in the case of an FSS <36. Expanded Disability Status Scale (EDSS) and Functional Independence Measure (FIM) were used as clinical outcome measures of the efficacy of the rehabilitation program. In our sample, an intensive, short-term rehabilitation treatment is able to determine a significant reduction of fatigue symptoms compared to untreated MS patients (p < 0.0001); however, the presence of fatigue at the beginning of the rehab program seems not to have any impact on the clinical and functional outcome of rehabilitation. An intensive inpatient rehabilitation trial decreases symptom of fatigue in MS patients; furthermore fatigue seems not to modify the amelioration of disability and impairment determined by a rehabilitation program. |
| | |
Authors:
|
Elda Judica; Filippo Martinelli Boneschi; Daniela Ungaro; Mauro Comola; Roberto Gatti; Giancarlo Comi; Paolo Rossi |
Related Documents
:
|
8119628 - Postgraduate education, training and specialization in haematology. 11603778 - Organization of tinnitus management in poland. 22484548 - Immigrant students' emotional and cognitive engagement at school: a multilevel analysis... 18632378 - Hamilton-jacobi-bellman equations and approximate dynamic programming on time scales. 9923138 - Producing physicians for south texas. 15985868 - Usefulness of the basis-32 in evaluating program level outcomes. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-1-15 |
Journal Detail:
|
Title: Journal of neurology Volume: - ISSN: 1432-1459 ISO Abbreviation: - Publication Date: 2011 Jan |
Date Detail:
|
Created Date: 2011-1-17 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0423161 Medline TA: J Neurol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Neurorehabilitation Unit, Department of Neurology, Institute of Experimental Neurology, Vita-Salute University, San Raffaele Scientific Institute, Milan, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Volume reduction in subcortical regions according to severity of Alzheimer's disease.
Next Document: Amelioration of selenite toxicity and cataractogenesis in cultured rat lenses by Vitex negundo.