Document Detail


Impact of false-positive newborn metabolic screening results on early health care utilization.
MedLine Citation:
PMID:  19661808     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To analyze the association between false-positive newborn screening results and health care utilization.
METHODS: We surveyed parents regarding their children's health care utilization. Parents of children who received false-positive newborn screening results were primarily enrolled by a screening laboratory in Pennsylvania. Parents of children with normal results were recruited through the Massachusetts birth registry. We used bivariate tests and multivariate regression to assess the association between newborn screening results and primary care utilization, emergency room use, and hospitalization by the age of 6 months.
RESULTS: Our sample included 200 children with false-positive results and 137 with normal results. Variation in recruitment strategies led to sample children with false-positive results being more likely to be non-white, have unmarried parents, and be of lower socioeconomic status. After adjusting for significant covariates, such as age, race, and socioeconomic status, there were no significant associations between newborn screening results and child health care utilization.
CONCLUSIONS: Despite the reported negative psychosocial effects of false-positive results, our study found no impact on early health care utilization. These results may assist in economic analyses of newborn screening as they suggest that medical costs associated with false-positive results are limited to the cost of diagnostic testing and follow-up.
Authors:
Ellen A Lipstein; James M Perrin; Susan E Waisbren; Lisa A Prosser
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Genetics in medicine : official journal of the American College of Medical Genetics     Volume:  11     ISSN:  1530-0366     ISO Abbreviation:  Genet. Med.     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-15     Completed Date:  2009-12-17     Revised Date:  2010-12-03    
Medline Journal Info:
Nlm Unique ID:  9815831     Medline TA:  Genet Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  716-21     Citation Subset:  IM    
Affiliation:
Center for Child and Adolescent Health Policy, MassGeneral Hospital for Children, Boston, Massachusetts 02114, USA. elipstein@partners.org
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MeSH Terms
Descriptor/Qualifier:
Delivery of Health Care / utilization*
False Positive Reactions
Female
Health Care Costs
Humans
Infant
Infant, Newborn
Infant, Newborn, Diseases / diagnosis,  epidemiology
Interviews as Topic
Male
Metabolic Diseases / diagnosis*,  epidemiology
Metabolism, Inborn Errors / diagnosis*,  epidemiology
Neonatal Screening / methods,  standards*
Sensitivity and Specificity
Grant Support
ID/Acronym/Agency:
5H46 MC00158//PHS HHS; R01 HG002085-01/HG/NHGRI NIH HHS; R01 HG002085-02/HG/NHGRI NIH HHS; R01 HG002085-03/HG/NHGRI NIH HHS; R01 HG002085-04/HG/NHGRI NIH HHS; R01 HG002085-05/HG/NHGRI NIH HHS; R01 HG002085-06/HG/NHGRI NIH HHS; R01 HG002085-06S1/HG/NHGRI NIH HHS; R01 HG02085/HG/NHGRI NIH HHS; T32 HP10018//PHS HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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