Document Detail


Impact of exercise training on arterial wall thickness in humans.
MedLine Citation:
PMID:  22150253     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Thickening of the carotid artery wall has been adopted as a surrogate marker of pre-clinical atherosclerosis, which is strongly related to increased cardiovascular risk. The cardioprotective effects of exercise training, including direct effects on vascular function and lumen dimension, have been consistently reported in asymptomatic subjects and those with cardiovascular risk factors and diseases. In the present review, we summarize evidence pertaining to the impact of exercise and physical activity on arterial wall remodelling of the carotid artery and peripheral arteries in the upper and lower limbs. We consider the potential role of exercise intensity, duration and modality in the context of putative mechanisms involved in wall remodelling, including haemodynamic forces. Finally, we discuss the impact of exercise training in terms of primary prevention of wall thickening in healthy subjects and remodelling of arteries in subjects with existing cardiovascular disease and risk factors.
Authors:
Dick H J Thijssen; N Timothy Cable; Daniel J Green
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Clinical science (London, England : 1979)     Volume:  122     ISSN:  1470-8736     ISO Abbreviation:  Clin. Sci.     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2011-12-13     Completed Date:  2012-01-31     Revised Date:  2013-06-27    
Medline Journal Info:
Nlm Unique ID:  7905731     Medline TA:  Clin Sci (Lond)     Country:  England    
Other Details:
Languages:  eng     Pagination:  311-22     Citation Subset:  IM    
Affiliation:
Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK.
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MeSH Terms
Descriptor/Qualifier:
Adaptation, Physiological
Cardiovascular Diseases / pathology,  physiopathology
Carotid Arteries / pathology,  physiology*
Carotid Intima-Media Thickness*
Exercise / physiology*
Humans
Physical Fitness / physiology
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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