| Impact of endothelium roughness on blood flow. | |
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MedLine Citation:
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PMID: 22300799 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Cell free layer (CFL), a plasma layer bounded by the red blood cell (RBC) core and the endothelium, plays an important physiological role. Its width affects the effective blood viscosity as well as the scavenging and production of nitric oxide (NO). Measurements of the CFL and its spatio-temporal variability are highly uncertain, exhibiting random fluctuations. Yet traditional models of blood flow and NO scavenging treat the CFL's bounding surfaces as deterministic and smooth. We investigate the effects of the endothelium roughness and uncertain (random) spatial variability on blood flow and the estimates of effective blood viscosity. |
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Authors:
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Sangwoo Park; Marcos Intaglietta; Daniel M Tartakovsky |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-26 |
Journal Detail:
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Title: Journal of theoretical biology Volume: - ISSN: 1095-8541 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-2-3 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0376342 Medline TA: J Theor Biol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Mechanical and Aerospace Engineering, University of California, San Diego, 9500 Gilman Dr., La Jolla, CA 92093, United States. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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