| Impact of dye injection on intracoronary pressure. | |
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MedLine Citation:
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PMID: 20449935 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: Coronary angiography is widely used to estimate coronary blood flow velocity, as in the TIMI frame count method. However, it is unknown to what extent the injection of dye elevates intracoronary pressure which may accelerate coronary blood flow velocity. In the present study, intracoronary pressure was measured during coronary angiography. METHODS AND RESULTS: In 25 patients with non-significant coronary lesions, assessed by fractional flow reserve measurement with a pressure guidewire, we recorded intracoronary pressure during dye injection for coronary angiography in the ostium of the coronary artery as well as distal to the lesion. There was a rise in mean intracoronary pressure during dye injection in both ostial and distal coronary arterial segments (from 90.8 +/- 17.2 mmHg to 96.8 +/- 18.5 mmHg and from 89.7 +/- 15.3 mmHg to 93.6 +/- 17.3 mmHg, respectively; p<0.001). Nevertheless, the absolute and relative increase in pressure was small (6.0 +/- 4.2 mmHg [6.7 +/- 4.9%] in the ostium, and 3.9 +/- 5.5 mmHg [4.2 +/- 5.7%] distally). CONCLUSIONS: In coronary arteries without significant stenosis, coronary angiography causes only a minor increase in intracoronary pressure. The limited impact of dye injection on intracoronary blood pressure confirms the value of coronary angiography for estimation of coronary flow velocity. |
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Authors:
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Martin Stoel; Jasveen Kandhai-Ragunath; Gert Van Houwelingen; Clemens Von Birgelen |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology Volume: 5 ISSN: 1969-6213 ISO Abbreviation: EuroIntervention Publication Date: 2009 Jun |
Date Detail:
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Created Date: 2010-05-07 Completed Date: 2010-08-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101251040 Medline TA: EuroIntervention Country: France |
Other Details:
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Languages: eng Pagination: 272-6 Citation Subset: IM |
Affiliation:
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Thorax Centre Twente, Medisch Spectrum Twente, Department of Cardiology, Enschede, The Netherlands. m.stoel@ziekenhuis-mst.nl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Blood Flow Velocity / drug effects Blood Pressure / drug effects* Contrast Media / administration & dosage*, diagnostic use Coronary Angiography* Coronary Artery Disease / physiopathology, radiography* Coronary Circulation / drug effects* Female Heart Catheterization Humans Injections, Intra-Arterial Male Middle Aged Triiodobenzoic Acids / administration & dosage*, diagnostic use |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Triiodobenzoic Acids; 92339-11-2/iodixanol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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