Document Detail

Impact of dry solids and bile acid concentrations on bile acid binding capacity of extruded oat cereals.
MedLine Citation:
PMID:  18754664     Owner:  NLM     Status:  MEDLINE    
Extruded breakfast cereals (EBC), processed from two oat lines, N979-5-2-4 (N979) and "Jim", with beta-glucan concentrations of 8.7 and 4.9%, respectively, were used to determine the impact of dry solids (DS) and bile acid (BA) concentrations on in vitro BA binding efficiency. A full fractional factorial design with levels for BA concentrations of 0.20, 0.47, 0.95, 2.37, and 4.73 micromol/g of total EBC slurry and for DS in the slurries of 0.8, 2, 3, and 4% (w/w) was selected. The absolute amount of BA bound (micromol) was measured for each trial in the experiment design. The percentage (%) of BA bound based on the total amount of BA added and BA bound per gram of DS of the EBC (micromol/g) were also presented and discussed. N979 in vitro digestion slurries had greater BA binding (micromol) than Jim slurries at different DS and BA concentrations, with greater differences at DS of 3% or above and at BA concentrations of 2.37 micromol/g or above. No difference in the absolute amount of BA bound (micromol) and percentage (%) BA bound occurred between the EBC slurries made from the two oat types at the lowest DS of 0.8% or the lowest BA concentration of 0.20 micromol/g. The efficiency of BA binding by beta-glucan in these two EBC became more distinguishable at 3% DS or above and BA concentrations of 2.37 micromol/g or above, indicating that these two conditions can be employed to measure BA capacities for similar foods. Also, the beta-glucan in the EBC produced from the N979 oat line was more soluble than that from the EBC produced from the Jim oat line. Thus, greater BA binding capacity may have been caused by both a greater amount of beta-glucan and a greater solubility of beta-glucan in N979 than in Jim EBC.
Ni Yao; Pamela J White; Jean-Luc Jannink; Sajid Alavi
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Publication Detail:
Type:  In Vitro; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2008-08-29
Journal Detail:
Title:  Journal of agricultural and food chemistry     Volume:  56     ISSN:  1520-5118     ISO Abbreviation:  J. Agric. Food Chem.     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-09-18     Completed Date:  2008-11-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0374755     Medline TA:  J Agric Food Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  8672-9     Citation Subset:  IM    
Department of Food Science and Human Nutrition, Iowa State University, Ames, Iowa 50011, USA.
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MeSH Terms
Avena sativa / chemistry*
Bile Acids and Salts / analysis*,  metabolism*
Cereals / chemistry*
Food Handling / methods*
beta-Glucans / analysis
Reg. No./Substance:
0/Bile Acids and Salts; 0/beta-Glucans

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