Document Detail

Impact of coronary disease after aortic valve replacement.
MedLine Citation:
PMID:  19643847     Owner:  NLM     Status:  MEDLINE    
Left ventricular dimensions tend to reduce after aortic valve replacement in patients with aortic stenosis. Whether concomitant coronary artery disease has an influence on postoperative ventricular dimensions has not been evaluated. Between 1998 and 2002, 112 patients underwent aortic valve replacement for aortic stenosis; 68 had isolated aortic valve replacement, and 44 had combined coronary artery bypass grafting. Left ventricular dimensions were assessed by echocardiography preoperatively and at 3 and 12 months postoperatively. Transvalvular mean gradient, left ventricular end-diastolic diameter, and left ventricular mass index decreased significantly postoperatively, while left ventricular ejection fraction improved. Preoperative left ventricular dimensions in patients with isolated aortic stenosis were worse than in those with aortic stenosis and coronary artery disease. After aortic valve replacement with coronary artery bypass, left ventricular mass index regression was less than that after valve replacement alone, and there was no improvement in ejection fraction. This suggests that coronary artery disease has a negative impact on postoperative myocardial recovery.
Jürg Grünenfelder; Iram Kilb; Andre Plass; Silvano Cominelli; Daniela Zeller; Michele Genoni
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Asian cardiovascular & thoracic annals     Volume:  17     ISSN:  1816-5370     ISO Abbreviation:  Asian Cardiovasc Thorac Ann     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-07-31     Completed Date:  2009-10-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9503417     Medline TA:  Asian Cardiovasc Thorac Ann     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  248-52     Citation Subset:  IM    
Clinic for Cardiovascular Surgery, University Hospital Zürich, Rämistrasse 100, CH-8091 Zürich, Switzerland.
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MeSH Terms
Age Factors
Aortic Valve / surgery
Aortic Valve Stenosis / physiopathology*,  surgery*
Coronary Artery Bypass
Coronary Disease / physiopathology*,  surgery
Diastole / physiology
Heart Valve Prosthesis*
Heart Ventricles / ultrasonography*
Postoperative Period
Preoperative Care
Stroke Volume / physiology
Ventricular Dysfunction, Left / physiopathology*,  ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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