| Impact of cocoa flavanol consumption on blood pressure responsiveness to exercise. | |
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MedLine Citation:
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PMID: 20082737 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Impaired endothelial vasodilatation may contribute to the exaggerated blood pressure (BP) responses to exercise in individuals who are overweight/obese. The present study investigated whether consumption of cocoa flavanols, which improve endothelium-dependent flow-mediated dilatation (FMD), can modify BP responsiveness to exercise. Twenty-one volunteers (eight females and thirteen males, 54.9 (se 2.2) years, BMI 31.6 (se 0.8) kg/m2, systolic BP 134 (se 2) mmHg, diastolic BP (DBP) 87 (se 2) mmHg) were randomised to consume single servings of either a high-flavanol (HF, 701 mg) or a low-flavanol (LF, 22 mg) cocoa beverage in a double-blind, cross-over design with 3-7-d washout between treatments. Two hours after cocoa consumption, FMD was measured, followed by continuous beat-to-beat assessment (Finapres) of BP before and during 10 min of cycling at 75 % of age-predicted maximum heart rate. Averaged data from two assessments on each type of beverage were compared by analysis of covariance using pre-exercise BP as the covariate. Pre-exercise BP was similar after taking LF and HF (153 (se 3)/88 (se 3) v. 153 (se 4)/87 (se 2) mmHg, respectively, P>0.05). However, the BP response to exercise (area under BP curve) was attenuated by HF compared with LF. BP increases were 68 % lower for DBP (P = 0.03) and 14 % lower for mean BP (P = 0.05). FMD measurements were higher after taking HF than after taking LF (6.1 (se 0.6) % v. 3.4 (se 0.5) %, P < 0.001). By facilitating vasodilation and attenuating exercise-induced increases in BP, cocoa flavanols may decrease cardiovascular risk and enhance the cardiovascular benefits of moderate intensity exercise in at-risk individuals. |
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Authors:
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Narelle M Berry; Kade Davison; Alison M Coates; Jonathan D Buckley; Peter R C Howe |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't Date: 2010-01-19 |
Journal Detail:
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Title: The British journal of nutrition Volume: 103 ISSN: 1475-2662 ISO Abbreviation: Br. J. Nutr. Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-05-17 Completed Date: 2010-06-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372547 Medline TA: Br J Nutr Country: England |
Other Details:
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Languages: eng Pagination: 1480-4 Citation Subset: IM |
Affiliation:
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School of Health Sciences, Nutritional Physiology Research Centre and ATN Centre for Metabolic Fitness, University of South Australia, GPO Box 2471, Adelaide, SA 5001, Australia. narelle.berry@unisa.edu.au |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Beverages Blood Pressure / drug effects*, physiology* Cacao / chemistry* Double-Blind Method Exercise / physiology* Female Flavonols / chemistry*, pharmacology* Humans Male Middle Aged Overweight |
| Chemical | |
Reg. No./Substance:
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0/Flavonols |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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