Document Detail

Impact of bifurcation lesions on clinical outcome and prognosis of primary angioplasty in acute myocardial infarction.
MedLine Citation:
PMID:  19112785     Owner:  NLM     Status:  MEDLINE    
AIMS: The aim of this study was to determine the impact of bifurcation lesions on outcomes after primary percutaneous intervention (PCI) for acute myocardial infarction. METHODS AND RESULTS: We retrospectively reviewed a single-centre database of 646 patients admitted for primary angioplasty within 12 hours after AMI. We compared baseline characteristics and outcomes between bifurcation and non-bifurcation lesions. Bifurcation lesions were found in 23% of patients. They predominantly involved the left anterior descending artery. Provisional T-stenting was used in 89.3% of patients (with stenting of the main branch in 82% and of both branches in 7.3%), side-branch protection in 54.6%, and final kissing balloon inflation in 33%. The procedural success rate was 92% for the main branch of bifurcation lesions compared with 93% for non-bifurcation lesions (P=0.65). Major adverse cardiac event (MACE) rates were comparable in the two groups: in-hospital MACE was 13.3% in the bifurcation group versus 11.4% in the non-bifurcation group (P=0.72), and the 1-year total MACE rate was 22.6% in the bifurcation group versus 19.5% in the non-bifurcation group (P=0.56). CONCLUSIONS: Bifurcation lesions are common in patients with AMI. In a population with AMI, immediate and mid-term outcomes of primary PCI were similar in patients with and without bifurcation lesions.
Diaa-Eldin Abdel-Hakim; Philippe Garot; Stéphane Champagne; Fathi Maklady; Ahmed el-Hawary; Jean-Luc Dubois-Randé; Pierre-François Lesault; Emmanuel Teiger
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology     Volume:  4     ISSN:  1774-024X     ISO Abbreviation:  -     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-12-30     Completed Date:  2009-02-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101251040     Medline TA:  EuroIntervention     Country:  France    
Other Details:
Languages:  eng     Pagination:  93-8     Citation Subset:  IM    
University Hospital Henri Mondor, Créteil, France.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary*
Coronary Angiography
Coronary Artery Disease / pathology,  radiography,  therapy
Coronary Vessels / pathology*
Databases, Factual
Follow-Up Studies
Middle Aged
Myocardial Infarction / pathology*,  radiography,  therapy*
Retrospective Studies
Treatment Outcome

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