Document Detail

Impact of antimicrobial resistance on regulatory policies in veterinary medicine: status report.
MedLine Citation:
PMID:  12646009     Owner:  NLM     Status:  MEDLINE    
Increasing resistance to antimicrobial agents is of growing concern to public health officials worldwide. The concern includes infections acquired in hospitals, community infections acquired in outpatient care settings, and resistant foodborne disease associated with drug use in food-producing animals. In the United States, a significant source of antimicrobial-resistant foodborne infections in humans is the acquisition of resistant bacteria originating from animals. The US Food and Drug Administration's (FDA's) goal in resolving the public health impact arising from the use of antimicrobial drugs in food-producing animals is to ensure that significant human antimicrobial therapies are not compromised or lost while providing for the safe use of antimicrobials in food animals. The FDA's approach to the problem is multipronged and innovative. The strategy includes revision of the pre-approval safety assessment for new animal drug applications, use of risk assessment to determine the human health effect resulting from the use of antimicrobials in food animals, robust monitoring for changes in susceptibilities among foodborne pathogens to drugs that are important both in human and veterinary medicine, research, and risk management.
Linda Tollefson; William T Flynn
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AAPS pharmSci     Volume:  4     ISSN:  1522-1059     ISO Abbreviation:  AAPS PharmSci     Publication Date:  2002  
Date Detail:
Created Date:  2003-03-20     Completed Date:  2003-03-31     Revised Date:  2013-06-09    
Medline Journal Info:
Nlm Unique ID:  100897065     Medline TA:  AAPS PharmSci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E37     Citation Subset:  IM    
Center for Veterinary Medicine, Food and Drug Administration, Rockville, MD 20855, USA.
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MeSH Terms
Drug Resistance, Microbial*
Legislation, Veterinary
Microbial Sensitivity Tests
United States
United States Food and Drug Administration
Veterinary Drugs / pharmacology*
Veterinary Medicine*
Reg. No./Substance:
0/Veterinary Drugs

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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