Document Detail

Impact of active immunisation against enteritis necroticans in Papua New Guinea.
MedLine Citation:
PMID:  1978034     Owner:  NLM     Status:  MEDLINE    
Enteritis necroticans, known locally as pigbel, has been a major cause of illness and death among children in the highlands of Papua New Guinea. After a successful trial of active immunisation against the beta toxin of the causative organism, Clostridium perfringens type C, immunisation of children was begun in 1980. The effects of the immunisation programme on pigbel admissions in 3 of the 5 major highland hospitals were assessed. In each of the centres studied the proportion of admissions due to enteritis necroticans dropped significantly after immunisation was introduced (p less than 0.001) and hospital admissions for pigbel in 1984-86, when immunisation was well established, were less than one fifth of previous figures.
G W Lawrence; D Lehmann; G Anian; C A Coakley; G Saleu; M J Barker; M W Davis
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Lancet     Volume:  336     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  1990 Nov 
Date Detail:
Created Date:  1990-12-11     Completed Date:  1990-12-11     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1165-7     Citation Subset:  AIM; IM    
Queensland Institute of Medical Research, Brisbane, Australia.
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MeSH Terms
Child, Preschool
Clostridium Infections / epidemiology,  microbiology,  pathology,  prevention & control*
Clostridium perfringens
Enteritis / epidemiology,  etiology,  microbiology,  pathology,  prevention & control*
Evaluation Studies as Topic
Hospitalization / statistics & numerical data
Immunization Schedule
Papua New Guinea / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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