| The Impact of Systemic Lupus Erythematosus on Women's Sexual Functioning. | |
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MedLine Citation:
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PMID: 21951616 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Introduction. The effect of systemic lupus erythematosus (SLE) on women's sexual functioning has been rarely assessed. Aim. The aim of this study is to evaluate the impact of SLE on women's sexual functioning. Methods. A total of 302 consecutive female outpatients with SLE were provided with a questionnaire composed of the Female Sexual Function Index (FSFI), questions for sociodemographic characteristics and comorbidities. Similarly, 2,159 hospital female employees were assessed as the control group. In patients, data of SLE duration and Sjögren's syndrome were derived from the chart records and the disease activity was assessed using the SLE Disease Activity Index 2000. Main Outcome Measures. The FSFI scores were compared between the patients and the controls. Correlates of the FSFI scores were determined in the patients. Results. Of 302 eligible patients, 92.4% (279/302) responded, in addition to 73.2% (1,580/2,159) of controls. Ninety-five percent (255/268) of the respondent patients were in no-to-mild SLE disease activity. Among the respondents, 171 (61.3%) patients and 930 (58.9%) controls were sexually active in the previous month, P = 0.446. Of the sexually active patients, 52.5% (85/162) had impaired sexual function (the FSFI total score < 26.55) and so did 47.1% (408/867) of the sexually active controls, P = 0.206. With adjustment of age group, marital status and education level, patients had lower FSFI scores than controls only in the domains of lubrication and pain. Significant risk factors for lower FSFI scores in the patients included persistent activity or flare of SLE, menstrual cycle disturbances, and vascular disease. With further adjustment of other risk factors, only vascular disease remained significant as a risk factor for impaired sexual function (odds ratio = 5.7; 95% confidence interval 1.6-20.1). Conclusion. When not in an exacerbation period, the impact of SLE on women's sexual functioning is not great and is related to vascular factors. Tseng J-C, Lu L-Y, Hu J-C, Wang L-F, Yen L-J, Wu H-C, and Jiann B-P. The impact of systemic lupus erythematosus on women's sexual functioning. J Sex Med **;**:**-**. |
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Authors:
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Jui-Cheng Tseng; Ling-Ying Lu; Jui-Chieh Hu; Li-Fong Wang; Ling-Jung Yen; Hsi-Chin Wu; Bang-Ping Jiann |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-23 |
Journal Detail:
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Title: The journal of sexual medicine Volume: - ISSN: 1743-6109 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101230693 Medline TA: J Sex Med Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2011 International Society for Sexual Medicine. |
Affiliation:
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Division of Allergy, Immunology and Rheumatology, Department of Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan Department of Urology, China Medical University Hospital; School of Medicine, China Medical University, Taichung, Taiwan Division of Urology, Department of Surgery and Division of Basic Medical Research, Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan. |
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