Document Detail

Impact of scar, viable myocardium, and epicardial fat on substrate identification of ventricular tachycardia in a case with nonischemic cardiomyopathy.
MedLine Citation:
PMID:  21883316     Owner:  NLM     Status:  MEDLINE    
A 56-year-old man with nonischemic cardiomyopathy underwent orthotopic cardiac transplantation after endocardial and epicardial radiofrequency catheter ablation for pleomorphic ventricular tachycardia. The myocardial substrate and epicardial fat were comprehensively analyzed with three-dimensional electroanatomic maps, late gadolinium enhanced ex-vivo cardiac magnetic resonance, and histological examination. The association of scar, viable myocardium, and epicardial fat with endocardial and epicardial electrogram voltage and duration was quantitatively defined. This case provides a unique opportunity to explore the reliability of electrical surrogates of scar in nonischemic cardiomyopathy.
Takeshi Sasaki; James Mudd; Charles Steenbergen; Menekhem M Zviman; Christopher F Miller; Saman Nazarian
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2011-09-02
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  35     ISSN:  1540-8159     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-11     Completed Date:  2013-05-27     Revised Date:  2014-03-19    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e345-8     Citation Subset:  IM    
Copyright Information:
©2011, The Authors. Journal compilation ©2012 Wiley Periodicals, Inc.
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MeSH Terms
Adipose Tissue
Body Surface Potential Mapping
Cardiomyopathies / physiopathology,  surgery*
Catheter Ablation / methods*
Cicatrix / physiopathology,  surgery*
Contrast Media / diagnostic use
Heart Transplantation*
Magnetic Resonance Imaging
Middle Aged
Pericardium / physiopathology,  surgery*
Tachycardia, Ventricular / physiopathology,  surgery*
Grant Support
K23 HL089333/HL/NHLBI NIH HHS; K23 HL089333-01A2/HL/NHLBI NIH HHS; K23 HL089333-02/HL/NHLBI NIH HHS; K23 HL089333-03/HL/NHLBI NIH HHS; K23HL089333/HL/NHLBI NIH HHS; R01 HL039752/HL/NHLBI NIH HHS
Reg. No./Substance:
0/Contrast Media

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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