| Impact of Progression of Parkinson's Disease on Drooling in Various Ethnic Groups. | |
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MedLine Citation:
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PMID: 22517489 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background/Aims: Drooling or sialorrhea is a common non-motor symptom of Parkinson's disease (PD), and is reported by 35-75% of patients. Drooling is primarily due to impaired swallowing rather than hypersecretion of saliva. In this study, we examined the prevalence of drooling in PD and its relation to various factors such as age, stage of disease, gender and ethnicity. Methods: A retrospective cohort chart analysis of 307 patients with idiopathic PD was conducted. These patients were seen in the Parkinson's Disease and Movement Disorders Clinic between 2005 and 2010. Results: 123 (40%) patients exhibited drooling. No correlation between age and development of drooling was observed. However, gender was found to be a significant factor in developing sialorrhea. Males are twice as more likely to develop sialorrhea than females. In addition, drooling becomes more prevalent with disease progression; Hoehn and Yahr stage 4 patients being the most at risk. Ethnicity and immigration status have no relationship in developing drooling. Conclusions: Sialorrhea is seen in a significant number of PD patients. This study, to the best of our knowledge, is the most extensive clinical assessment of drooling in PD to date. |
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Authors:
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Abdul Qayyum Rana; Muhammad Saad Yousuf; Naeem Awan; Abdul Fattah |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-4-20 |
Journal Detail:
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Title: European neurology Volume: 67 ISSN: 1421-9913 ISO Abbreviation: - Publication Date: 2012 Apr |
Date Detail:
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Created Date: 2012-4-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0150760 Medline TA: Eur Neurol Country: - |
Other Details:
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Languages: ENG Pagination: 312-314 Citation Subset: - |
Copyright Information:
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Copyright © 2012 S. Karger AG, Basel. |
Affiliation:
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Parkinson's Clinic of Eastern Toronto and Movement Disorders Centre, Scarborough, Ont., Canada. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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