| The impact of polyunsaturated fatty acids in reducing child attention deficit and hyperactivity disorders. | |
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MedLine Citation:
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PMID: 20424008 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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OBJECTIVES: To review the impact of polyunsaturated fatty acids (PUFA) in reducing ADHD symptoms in children. METHODS: Peer-reviewed experimental literature published from 1980 to Mai 2009 is consulted (Psychinfo, Medline, and resulting reference lists). RESULTS: Placebo-controlled studies with ADHD or hyperactive children show no effects on behaviors or cognition when only n-6 (omega-6) PUFA, only docosahexaenoic acid (DHA), or n-6 and n-3 (omega-3) short-chain PUFA are supplemented. Yet three out of four studies suggest that a combination of long-chain n-3 and n-6 fatty acids (DHA, eicosapentaenoic acid [EPA], and gamma-linolenic acid [GLA]) supplemented daily for 3 to 4 months could lead to a reduction in ADHD symptomatology. Results on cognitive outcomes are inconsistent. CONCLUSIONS: Evidence is too limited to reach definitive conclusions but suggests that research on the impact of long-chain PUFA (n-3 and n-6) should continue with special focus on individual differences (genetic and fatty acid markers), mechanisms (brain imaging), and new enhanced methods of systematic observations of behaviors. |
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Authors:
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Catherine Transler; Ans Eilander; Siobhan Mitchell; Nelly van de Meer |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-04-27 |
Journal Detail:
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Title: Journal of attention disorders Volume: 14 ISSN: 1557-1246 ISO Abbreviation: J Atten Disord Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-27 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9615686 Medline TA: J Atten Disord Country: United States |
Other Details:
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Languages: eng Pagination: 232-46 Citation Subset: IM |
Affiliation:
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Unilever Food and Health Research Institute, the Netherlands. catherine.transler@unilever.com |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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