Document Detail


Impact of Obesity and the Obesity Paradox on Prevalence and Prognosis in Heart Failure.
MedLine Citation:
PMID:  24621833     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Obesity has reached epidemic proportions in the United States and worldwide. Considering the adverse effects of obesity on left ventricular (LV) structure, diastolic and systolic function, and other risk factors for heart failure (HF), including hypertension and coronary heart disease, HF incidence and prevalence, not surprisingly, is markedly increased in obese patients. Nevertheless, as with most other cardiovascular diseases, numerous studies have documented an obesity paradox, in which overweight and obese patients, defined by body mass index, percent body fat, or central obesity, demonstrate a better prognosis compared with lean or underweight HF patients. This review will describe the data on obesity in the context of cardiopulmonary exercise testing in HF. Additionally, the implications of obesity on LV assist devices and heart transplantation are reviewed. Finally, despite the obesity paradox, we address the current state of weight reduction in HF.
Authors:
Carl J Lavie; Martin A Alpert; Ross Arena; Mandeep R Mehra; Richard V Milani; Hector O Ventura
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Publication Detail:
Type:  REVIEW     Date:  2013-4-1
Journal Detail:
Title:  JACC. Heart failure     Volume:  1     ISSN:  2213-1787     ISO Abbreviation:  JACC Heart Fail     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2014-3-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101598241     Medline TA:  JACC Heart Fail     Country:  -    
Other Details:
Languages:  ENG     Pagination:  93-102     Citation Subset:  -    
Copyright Information:
Copyright © 2013 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.
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