| Impact of modified treatment in echocardiographically confirmed pseudo-pulseless electrical activity in out-of-hospital cardiac arrest patients with constant end-tidal carbon dioxide pressure during compression pauses. | |
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MedLine Citation:
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PMID: 20926019 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study evaluated the ability of focused echocardiography (FE) and capnography to differentiate between pulseless electrical activity (PEA) and pseudo-PEA in out-of-hospital cardiac arrest, and the potential survival benefits with modified treatment. In PEA patients with stable end-tidal carbon dioxide pressure (P(et)CO(2)) during the compression pause and concomitant FE showing cardiac kinetic activity, the compression pause was prolonged for 15 s and an additional 20 IU vasopressin was administered. If pulselessness persisted, compressions were continued. Fifteen of the 16 patients studied (94%) achieved restoration of spontaneous circulation (ROSC); eight patients (50%) attained a good neurological outcome (Cerebral Performance Category 1 - 2). In an historical PEA group with stable P(et)CO(2) values (n = 48), ROSC was achieved in 26 patients (54%); four patients (8%) attained Cerebral Performance Category 1 - 2. Echocardiographical verification of the pseudo-PEA state enabled additional vasopressor treatment and cessation of chest compressions, and was associated with significantly higher rates of ROSC, survival to discharge and good neurological outcome. |
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Authors:
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G Prosen; M Križmarić; J Završnik; S Grmec |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of international medical research Volume: 38 ISSN: 0300-0605 ISO Abbreviation: J. Int. Med. Res. Publication Date: 2010 Jul-Aug |
Date Detail:
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Created Date: 2010-10-07 Completed Date: 2010-12-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0346411 Medline TA: J Int Med Res Country: England |
Other Details:
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Languages: eng Pagination: 1458-67 Citation Subset: IM |
Affiliation:
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Centre for Emergency Medicine Maribor, University of Maribor, Maribor, Slovenia. gregorprosen@gmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Carbon Dioxide / metabolism* Cardiopulmonary Resuscitation / methods* Demography Echocardiography Electricity* Female Humans Male Middle Aged Out-of-Hospital Cardiac Arrest / physiopathology*, ultrasonography* Pressure* Pulse Tidal Volume / physiology* |
| Chemical | |
Reg. No./Substance:
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124-38-9/Carbon Dioxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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