| Impact of the metabolic syndrome on the clinical outcome of patients with acute ST-elevation myocardial infarction. | |
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MedLine Citation:
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PMID: 20890426 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We sought to determine the prevalence of metabolic syndrome (MS) in patients with acute myocardial infarction and its effect on clinical outcomes. Employing data from the Korea Acute Myocardial Infarction Registry, a total of 1,990 patients suffered from acute ST-elevation myocardial infarction (STEMI) between November 2005 and December 2006 were categorized according to the National Cholesterol Education Program-Adult Treatment Panel III criteria of MS. Primary study outcomes included major adverse cardiac events (MACE) during one-year follow-up. Patients were grouped based on existence of MS: group I: MS (n=1,182, 777 men, 62.8±12.3 yr); group II: Non-MS (n=808, 675 men, 64.2±13.1 yr). Group I showed lower left ventricular ejection fraction (LVEF) (P=0.005). There were no differences between two groups in the coronary angiographic findings except for multivessel involvement (P=0.01). The incidence of in-hospital death was higher in group I than in group II (P=0.047), but the rates of composite MACE during one-year clinical follow-up showed no significant differences. Multivariate analysis showed that low LVEF, old age, MS, low high density lipoprotein cholesterol and multivessel involvement were associated with high in-hospital death rate. In conclusion, MS is an important predictor for in-hospital death in patients with STEMI. |
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Authors:
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Min Goo Lee; Myung Ho Jeong; Youngkeun Ahn; Shung Chull Chae; Seung Ho Hur; Taek Jong Hong; Young Jo Kim; In Whan Seong; Jei Keon Chae; Jay Young Rhew; In Ho Chae; Myeong Chan Cho; Jang Ho Bae; Seung Woon Rha; Chong Jin Kim; Donghoon Choi; Yang Soo Jang; Junghan Yoon; Wook Sung Chung; Jeong Gwan Cho; Ki Bae Seung; Seung Jung Park |
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Publication Detail:
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Type: Journal Article Date: 2010-09-17 |
Journal Detail:
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Title: Journal of Korean medical science Volume: 25 ISSN: 1598-6357 ISO Abbreviation: J. Korean Med. Sci. Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-04 Completed Date: 2011-02-17 Revised Date: 2013-05-29 |
Medline Journal Info:
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Nlm Unique ID: 8703518 Medline TA: J Korean Med Sci Country: Korea (South) |
Other Details:
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Languages: eng Pagination: 1456-61 Citation Subset: IM |
Affiliation:
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The Heart Center of Chonnam National University Hospital, Gwangju, Korea. |
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Age Factors Aged C-Reactive Protein / analysis Cholesterol, LDL / blood Coronary Angiography Female Humans Male Metabolic Syndrome X / complications*, epidemiology Middle Aged Multivariate Analysis Myocardial Infarction / complications*, mortality, therapy Predictive Value of Tests Prognosis Treatment Outcome Ventricular Dysfunction, Left / complications, physiopathology |
| Chemical | |
Reg. No./Substance:
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0/Cholesterol, LDL; 9007-41-4/C-Reactive Protein |
| Comments/Corrections | |
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