Document Detail


The Impact of Meningococcal Polymerase Chain Reaction Testing on Laboratory Confirmation of Invasive Meningococcal Disease.
MedLine Citation:
PMID:  22173139     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Laboratory methods of diagnosis were examined for 266 children with invasive meningococcal disease (IMD). Seventy-five (36%) of 207 cases with bloodstream infection (BSI) had both positive blood culture and blood meningococcal PCR, 130 (63%) negative blood culture and positive blood PCR, and 2 (1%) had positive blood culture and negative blood PCR. 63% of cases were diagnosed by PCR alone.
Authors:
Richard J Drew; Cilian O Maoldomhnaigh; Patrick J Gavin; Nicola Oʼ Sullivan; Karina M Butler; Mary Cafferkey
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-14
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  -     ISSN:  1532-0987     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
1Irish Meningococcal and Meningitis Reference Laboratory (IMMRL), The Children's University Hospital, Temple Street, Dublin 2Department of Clinical Microbiology, The Children's University Hospital, Temple Street, Dublin 3Department of Paediatric Infectious Diseases, Our Lady's Children's Hospital, Crumlin, Dublin 4Department of Paediatric Infectious Diseases, The Children's University Hospital, Temple Street, Dublin 5Department of Clinical Microbiology, The Royal College of Surgeons in Ireland, Dublin, Ireland.
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