Document Detail

The Impact of a Ketogenic Diet and Liver Dysfunction on Serum Very Long-Chain Fatty Acids Levels.
MedLine Citation:
PMID:  23371825     Owner:  NLM     Status:  Publisher    
Peroxisomes play an essential role in mammalian cellular metabolism, particularly in oxidation fatty acid pathways. Serum very long-chain fatty acids (VLCFA), the main biochemical diagnostic parameters for peroxisomal disorders, were examined in 25 neurological patients with epilepsy on a ketogenic diet and 27 patients with liver dysfunction. The data show that patients on a ketogenic diet have increased levels of C22:0 and C24:0, but not C26:0, and normal C24:0/C22:0 and C26:0/C22:0. Patients with liver insufficiency showed a slightly elevated level of C26:0, a normal level of C24:0 and a decreased level of C22:0; thus in 21/27 the ratio of C24:0/C22:0 was increased and 15/27 the ratio of C26:0/C22:0 was increased.
T J Stradomska; M Bachański; J Pawłowska; M Syczewska; A Stolarczyk; A Tylki-Szymańska
Related Documents :
23820405 - Estimation of fish and omega-3 fatty acid intake in pediatric nonalcoholic fatty liver ...
24294945 - Reactive oxygen and nitrogen species in steatotic hepatocytes: a molecular perspective ...
24612645 - Fatty acids increase hepatitis b virus x protein stabilization and hbx-induced inflamma...
17883945 - Synthesis and antitussive evaluation of verticinone-cholic acid salt, a novel and poten...
375 - The effect of tryptophan administration on fatty acid synthesis in the livers of rats u...
12738195 - Safety evaluation of sources of docosahexaenoic acid and arachidonic acid for use in in...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-31
Journal Detail:
Title:  Lipids     Volume:  -     ISSN:  1558-9307     ISO Abbreviation:  Lipids     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-2-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0060450     Medline TA:  Lipids     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Biochemistry and Experimental Medicine, The Children's Memorial Health Institute, Al. Dzieci Polskich 20, 04-730, Warsaw, Poland,
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Toxicity and quality of life of Korean breast cancer patients treated with docetaxel-containing chem...
Next Document:  Bone Health of Apprentice Jockeys Using Peripheral Quantitative Computed Tomography.