| Impact of Hispanic ethnicity on the likelihood of developing postoperative atrial fibrillation. | |
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MedLine Citation:
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PMID: 16768058 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: A recent multicenter observational study of 4,657 patients reported a 52% lower risk of postcardiothoracic surgery (CTS) atrial fibrillation (AF) among South American vs United States patients. This study did not evaluate whether the decreased incidence in AF was attributable to differing ethnicity (Hispanic vs Caucasian) or to another cause. METHODS: A cohort study of CTS patients at Hartford Hospital was undertaken to evaluate whether Hispanic patients had a lower incidence of post-CTS AF than Caucasians. First, Hispanic patients were compared to the total Caucasian population. Then differences in important baseline predictors of AF were probed between groups. Finally, Hispanic patients undergoing CTS were matched (1:4 matching) with Caucasian patients based upon known predictors of post-CTS AF including age >70 years, valvular surgery, AF history, previous CTS, peripheral vascular disease, gender, pre-CTS digoxin and beta-blocker intolerance. RESULTS: In the total population [n = 2,739, with 97 (3.5%) Hispanics, 66.6 +/- 11.6 years, 70.9% male, 66.9% valve surgery], Hispanics were 38% less likely to develop AF (15.5% vs 24.8%, P = 0.035). However, the Hispanic patients were 11.9 years younger (P< 0.001) with 14.7% more women (P = 0.002) which reduces the risk of post-CTS AF; they also had a 12.8% higher risk of valvular surgery (P = 0.009) which is known to enhance the risk. When these factors and other important variables were matched for, a total of 485 patients (n = 97 Hispanics, 388 Caucasian) were evaluated (55.8 +/- 13.1 years, 57.3% male, 45.4% valvular surgery). Hispanic and Caucasian patients had a similar incidence of post-CTS AF (15.5% vs 18.3%, P = 0.513). CONCLUSION: Hispanic patients do not have an innately lower risk of post-CTS AF than Caucasians. |
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Authors:
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Kristen A Gryskiewicz; Effie L Gillespie; C Michael White; Jeffrey Kluger; Robert Gallagher; Craig I Coleman |
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Publication Detail:
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Type: Comparative Study; Journal Article; Multicenter Study |
Journal Detail:
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Title: Connecticut medicine Volume: 70 ISSN: 0010-6178 ISO Abbreviation: Conn Med Publication Date: 2006 Feb |
Date Detail:
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Created Date: 2006-06-13 Completed Date: 2006-07-13 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372745 Medline TA: Conn Med Country: United States |
Other Details:
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Languages: eng Pagination: 77-9 Citation Subset: IM |
Affiliation:
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University of Connecticut School of Pharmacy, Hartford, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Atrial Fibrillation / epidemiology, ethnology*, etiology Cardiac Surgical Procedures / adverse effects* Connecticut / epidemiology European Continental Ancestry Group / statistics & numerical data Female Hispanic Americans / statistics & numerical data* Hospitals Humans Incidence Male Middle Aged Postoperative Complications / epidemiology* Prospective Studies Risk Assessment* Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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