Document Detail


Impact of Hispanic ethnicity on the likelihood of developing postoperative atrial fibrillation.
MedLine Citation:
PMID:  16768058     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: A recent multicenter observational study of 4,657 patients reported a 52% lower risk of postcardiothoracic surgery (CTS) atrial fibrillation (AF) among South American vs United States patients. This study did not evaluate whether the decreased incidence in AF was attributable to differing ethnicity (Hispanic vs Caucasian) or to another cause. METHODS: A cohort study of CTS patients at Hartford Hospital was undertaken to evaluate whether Hispanic patients had a lower incidence of post-CTS AF than Caucasians. First, Hispanic patients were compared to the total Caucasian population. Then differences in important baseline predictors of AF were probed between groups. Finally, Hispanic patients undergoing CTS were matched (1:4 matching) with Caucasian patients based upon known predictors of post-CTS AF including age >70 years, valvular surgery, AF history, previous CTS, peripheral vascular disease, gender, pre-CTS digoxin and beta-blocker intolerance. RESULTS: In the total population [n = 2,739, with 97 (3.5%) Hispanics, 66.6 +/- 11.6 years, 70.9% male, 66.9% valve surgery], Hispanics were 38% less likely to develop AF (15.5% vs 24.8%, P = 0.035). However, the Hispanic patients were 11.9 years younger (P< 0.001) with 14.7% more women (P = 0.002) which reduces the risk of post-CTS AF; they also had a 12.8% higher risk of valvular surgery (P = 0.009) which is known to enhance the risk. When these factors and other important variables were matched for, a total of 485 patients (n = 97 Hispanics, 388 Caucasian) were evaluated (55.8 +/- 13.1 years, 57.3% male, 45.4% valvular surgery). Hispanic and Caucasian patients had a similar incidence of post-CTS AF (15.5% vs 18.3%, P = 0.513). CONCLUSION: Hispanic patients do not have an innately lower risk of post-CTS AF than Caucasians.
Authors:
Kristen A Gryskiewicz; Effie L Gillespie; C Michael White; Jeffrey Kluger; Robert Gallagher; Craig I Coleman
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Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study    
Journal Detail:
Title:  Connecticut medicine     Volume:  70     ISSN:  0010-6178     ISO Abbreviation:  Conn Med     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-06-13     Completed Date:  2006-07-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372745     Medline TA:  Conn Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  77-9     Citation Subset:  IM    
Affiliation:
University of Connecticut School of Pharmacy, Hartford, USA.
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MeSH Terms
Descriptor/Qualifier:
Aged
Atrial Fibrillation / epidemiology,  ethnology*,  etiology
Cardiac Surgical Procedures / adverse effects*
Connecticut / epidemiology
European Continental Ancestry Group / statistics & numerical data
Female
Hispanic Americans / statistics & numerical data*
Hospitals
Humans
Incidence
Male
Middle Aged
Postoperative Complications / epidemiology*
Prospective Studies
Risk Assessment*
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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