| The impact of erectile dysfunction on the quality of life of men undergoing hemodialysis and its association with depression. | |
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MedLine Citation:
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PMID: 20807331 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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INTRODUCTION: Erectile dysfunction (ED) is highly prevalent among men undergoing hemodialysis. AIM: This study was performed to identify the influence of ED on the patient's quality of life (QoL) and to evaluate the influence of depression on erectile function of these patients. MAIN OUTCOME MEASURES: For this multicenter cross-sectional study, 275 patients were interviewed through questionnaires: the five-item version of the International Index of Erectile Function was used for diagnosing and classifying ED; the Medical Outcomes Study Questionnaire 36-Item Short Form Health Survey (SF-36) for scoring QoL; and the Hospital Anxiety and Depression Scale (HADS) to evaluate depressive symptoms. Linear regression was used to examine the associations between some of the variables and ED. Predialytic biochemical and hematological parameters were determined during the longer interdialytic period. RESULTS: Patients had a mean age of 48.6 ± 12.8 years, and the ED prevalence was 72.3%. Advanced age, diabetes and depression score were independent risk factors for the development of ED as confirmed by linear regression (P < 0.001, P = 0.002, and P < 0.001, respectively). QoL was worse among patients with any degree of ED, and the scores were statistically significant for overall health rating (P = 0.016), physical composite score (P = 0.003), bodily pain (P = 0.042), physical functioning (P < 0.001), and vitality (P = 0.005). Furthermore, more severe forms of ED were associated with a lower QoL. After adjustment for some variables, such as age, time under dialysis, hemoglobin, albumin, parathyroid hormone, Kt/V, and depression, linear regression showed that domains related to poorer physical functioning (P = 0.047) and decreased vitality (P = 0.009) were significantly related to ED. CONCLUSION: Depression is an important trigger for the development of ED in hemodialysis patients, and this sexual condition is an independent risk factor for their poor QoL. |
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Authors:
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Gisele Vajgel Fernandes; Rondineli Roberto dos Santos; Waldênio Soares; Louize Gomes de Lima; Breno Santiago de Macêdo; João Eduardo da Fonte; Bruno Silva Peixoto de Carvalho; Sandra Neiva Coelho; Adriano Almeida Calado |
Publication Detail:
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Type: Journal Article Date: 2010-08-30 |
Journal Detail:
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Title: The journal of sexual medicine Volume: 7 ISSN: 1743-6109 ISO Abbreviation: J Sex Med Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101230693 Medline TA: J Sex Med Country: United States |
Other Details:
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Languages: eng Pagination: 4003-10 Citation Subset: IM |
Copyright Information:
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© 2010 International Society for Sexual Medicine. |
Affiliation:
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Department of Urology, State University of Pernambuco, Recife, Brazil. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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