Document Detail


Impact of Duffy antigen receptor for chemokine gene expression on mandibular bone density in menopausal women.
MedLine Citation:
PMID:  22910367     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The aim of this study is to demonstrate the relationship between the expression of the Duffy antigen receptor for chemokine (DARC) gene in peripheral blood leucocytes and epithelial cells of the oral cavity and the level of bone mineral density (BMD) in the mandible of women during menopause. A special radiographic method for measuring mandible density was used. Studies of DARC gene expression in the epithelial cells of the oral cavity and peripheral blood leucocytes did not confirm a significant correlation between expression of DARC and the level of BMD of the mandible in patients from the study groups, both in assessing the level of gene expression (ΔC(T) DARC) in the epithelium and leucocytes, as well as the value of relative expression (RQ) of DARC epithelium and lymphocytes. Significant differences were found between the values of ΔC(T) DARC marked in leucocytes and the epithelium of the control and study groups. Regarding RQ, the tests showed no significant differences between the values marked in the epithelial cells and leucocytes. The influence of DARC gene expression on bone mineral density of the mandible was not confirmed.
Authors:
W Swiątkowski; M Rahnama; J Kocki; A Swiatkowską
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-18
Journal Detail:
Title:  International journal of oral and maxillofacial surgery     Volume:  -     ISSN:  1399-0020     ISO Abbreviation:  Int J Oral Maxillofac Surg     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8605826     Medline TA:  Int J Oral Maxillofac Surg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
Affiliation:
Department of Oral Surgery, Medical University of Lublin, Lublin, Poland.
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