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Impact of Cigarette Smoking on Conversion from Clinically Isolated Syndrome to Clinically Definite Multiple Sclerosis.
MedLine Citation:
PMID:  23302010     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
ABSTRACT Multiple sclerosis (MS) is known to be influenced by various environmental factors including cigarette smoking. To identify the impact of smoking on conversion from clinically isolated syndrome (CIS) to clinically definite MS (CDMS), 95 consecutive uniformly-treated smoker (n = 31) and non-smoker (n = 64) CIS patients were evaluated retrospectively. The smoker CIS patients did not differ from non-smokers by means of demographic and clinical findings. In addition, there was no difference between the two groups with respect to rate and time of conversion to CDMS. However, white matter lesions were detected in MRIs of all smoking versus 54 of 64 (63.5%) non-smoking CIS patients (p = 0.02). Our results show that smoking does not predict conversion from CIS to CDMS. However, smoking may be associated with the appearance of white matter lesions on MRI at CIS onset.
Authors:
Adalet Arikanoglu; Erkingül Shugaiv; Erdem Tüzün; Mefkure Eraksoy
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-10
Journal Detail:
Title:  The International journal of neuroscience     Volume:  -     ISSN:  1563-5279     ISO Abbreviation:  Int. J. Neurosci.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0270707     Medline TA:  Int J Neurosci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
1Department of Neurology, Faculty of Medicine, Dicle University , Diyarbakır , Turkey.
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