| Impact of Body Mass Index on Clinical Outcome in Patients Hospitalized With Congestive Heart Failure. | |
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MedLine Citation:
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PMID: 22094909 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background: Obesity has recently been shown to have a favorable effect on the prognosis of patients with congestive heart failure (CHF), but only a few such studies are available in Japan. The purpose of the present study was to investigate whether the obesity paradox is still present after adjusting for CHF characteristics. Methods and Results: A total of 219 patients hospitalized with CHF were reviewed, and the impact of body mass index (BMI) on prognosis was examined. Patients were divided into 4 groups according to BMI quartiles. The endpoint was defined as all-cause death or unplanned CHF hospitalization. According to univariate analysis, a higher BMI was associated with better outcomes. High-BMI patients were younger, likely to be male, and had a higher prevalence of hypertension and diabetes. The plasma B-type natriuretic peptide (BNP) levels and blood urea nitrogen (BUN) levels were lower, while the serum hemoglobin and sodium levels were higher in high-BMI patients. The prevalence of atrial fibrillation was lower in high-BMI patients. Predictors for all-cause death or CHF hospitalization based on univariate analysis were age, prior CHF hospitalization, estimated glomerular filtration rate, plasma BNP levels, BUN levels, and serum hemoglobin and sodium levels. According to multivariate analysis, a high BMI was still associated with better outcomes. Conclusions: High BMI was associated with better clinical outcomes in Japanese CHF patients. |
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Authors:
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Kimiaki Komukai; Kosuke Minai; Satoshi Arase; Takayuki Ogawa; Tokiko Nakane; Tomohisa Nagoshi; Yosuke Kayama; Yuichi Abe; Satoshi Morimoto; Kazuo Ogawa; Shinya Fujii; Hiroshi Sekiyama; Taro Date; Makoto Kawai; Kenichi Hongo; Ikuo Taniguchi; Michihiro Yoshimura |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-11-16 |
Journal Detail:
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Title: Circulation journal : official journal of the Japanese Circulation Society Volume: - ISSN: 1347-4820 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-11-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101137683 Medline TA: Circ J Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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