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Impact of Admission Anemia, C-Reactive Protein and Mean Platelet Volume on Short Term Mortality in Patients with Acute St-Elevation Myocardial Infarction Treated with Primary Angioplasty.
MedLine Citation:
PMID:  22659059     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVES: To investigate admission anemia, C-reactive protein (CRP) and mean platelet volume (MPV) together as prognostic markers in ST-elevation myocardial infarction (STEMI). DESIGN AND METHODS: Baseline hemoglobin, CRP and MPV were determined in 543 patients with acute STEMI to whom primary angioplasty was performed and evaluated for short term mortality (30days). RESULTS: After multivariate analysis anemia (odds ratio 2.69, 95% confidence interval 1.24-5.86) and CRP (odds ratio 3.40, 95% confidence interval 1.13-10.22) remained significant independent predictors of short-term mortality. Addition of anemia and CRP to PAMI risk score improved prediction of short-term outcome; area under ROC curve rose from 0.76 to 0.87 (p<0.001). CONCLUSION: Better ability to determine 30-day mortality was obtained when anemia and CRP were incorporated into the PAMI risk score.
Authors:
Mislav Vrsalovic; Hrvoje Pintaric; Zdravko Babic; Marin Pavlov; Ana Vrsalovic Presecki; Biserka Getaldic; Nada Vrkic; Vjeran Nikolic Heitzler
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-31
Journal Detail:
Title:  Clinical biochemistry     Volume:  -     ISSN:  1873-2933     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-6-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0133660     Medline TA:  Clin Biochem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012. Published by Elsevier Inc.
Affiliation:
School of Medicine, University of Zagreb, Croatia; Department of Cardiology, Sestre Milosrdnice University Hospital, Zagreb, Croatia.
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