| Immunotoxic damage in floriculturists exposed to pesticide mixtures. | |
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MedLine Citation:
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PMID: 23030438 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The aim of the present work was to determine if the use of pesticide mixtures produced alterations in immunotoxicity biomarkers. The study was undertaken in three groups: the first group consisted of 38 floriculturists, the second comprised 38 vendors of the local market, and the last comprised 33 non-exposed persons from another locality. The determinations included haematocrit, mean cellular volume, hemoglobin, number of erythrocytes and leukocytes, immunoglobulins (IgA, IgG, IgM, and IgE), percentage of T-lymphocytes, and mitotic index from lymphocyte cultures with and without phytohaemagglutinin (PHA). The obtained results indicated the following: (i) in the level of the studied immunoglobulins, the results were within the reference values; (ii) there was a reduction in the amount of T-lymphocytes in the floriculturists in comparison with the determined in the other two groups; (iii) there was a decrease in the mitotic index of PHA-stimulated lymphocyte cultures of floriculturists and vendors in relation to the value of the control group; (iv) there was an increase in the mitotic index of unstimulated lymphocytes of floriculturists compared with the lymphocytes of the other two groups; and (v) there was no correlation between the results and the personal characteristics of the studied individuals. Our results established an immunotoxic effect in the floriculturists exposed to pesticides. |
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Authors:
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Julieta Castillo-Cadena; Ana Laura González-Mercado; Nancy Hernández-Caballero; Eduardo Ramírez-San Juan; Isela Alvarez-González; Eduardo Madrigal-Bujaidar |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes Volume: 48 ISSN: 1532-4109 ISO Abbreviation: J Environ Sci Health B Publication Date: 2013 |
Date Detail:
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Created Date: 2012-10-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7607167 Medline TA: J Environ Sci Health B Country: England |
Other Details:
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Languages: eng Pagination: 33-9 Citation Subset: IM |
Affiliation:
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a Laboratorio de Genética, Facultad de Química, Universidad Autónoma del Estado de México , México. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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