| Immunotherapy for metastatic melanoma. | |
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MedLine Citation:
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PMID: 22006439 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Melanoma has traditionally been considered an immunogenic tumor. A number of approaches have been studied for enhancement of anti-tumor immunity. The first cytokine approved for the treatment of metastatic melanoma, interleukin-2, has resulted in prolonged responses in a small subset of patients, providing hope that immunotherapy might be useful for this disease. Ipilimumab, a monoclonal antibody to CTLA-4 was recently approved, and a number of other promising investigational approaches are currently being pursued. This manuscript discusses more recent advances in the treatment of melanoma employing a variety of immune-enhancing approaches. J. Cell. Biochem. © 2011 Wiley Periodicals, Inc. |
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Authors:
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Christopher Zito; Harriet M Kluger |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-10-17 |
Journal Detail:
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Title: Journal of cellular biochemistry Volume: - ISSN: 1097-4644 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8205768 Medline TA: J Cell Biochem Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Wiley Periodicals, Inc. |
Affiliation:
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Yale Cancer Center, Yale School of Medicine, 333 Cedar Street, New Haven, CT, 06451. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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