| Immunotactoid-like glomerulopathy with massive fibrillary deposits in liver and bone marrow in monoclonal gammopathy. | |
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MedLine Citation:
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PMID: 8955765 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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At autopsy, massive nonamyloid fibrillar deposits, immunoreactive to IgG and kappa light chain, were found in glomeruli, liver, and bone marrow of a 72-year-old woman. The patient suffered from severe nephrotic syndrome, hepatomegaly and cholestasis, normochromic anemia, and IgG kappa monoclonal gammopathy. Fibrillary glomerulopathies, most often denoted as fibrillary glomerulonephritis or immunotactoid glomerulopathy, are generally considered to have deposits restricted to the glomeruli. However, this study indicates that fibrillary deposits may be a systemic manifestation of fibrillary glomerulonephritis or immunotactoid glomerulopathy, at least when the patient is suffering from a monoclonal gammopathy. |
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Authors:
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E H Strøm; N Hurwitz; A C Mayr; P H Krause; M J Mihatsch |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: American journal of nephrology Volume: 16 ISSN: 0250-8095 ISO Abbreviation: Am. J. Nephrol. Publication Date: 1996 |
Date Detail:
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Created Date: 1997-03-04 Completed Date: 1997-03-04 Revised Date: 2007-02-14 |
Medline Journal Info:
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Nlm Unique ID: 8109361 Medline TA: Am J Nephrol Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 523-8 Citation Subset: IM |
Affiliation:
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Institute for Pathology, University of Basel, Switzerland. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Bone Marrow / immunology, pathology* Female Glomerulonephritis / complications, pathology* Humans Immunoglobulins / analysis Immunohistochemistry Kidney / immunology, pathology Liver / immunology, pathology* Microscopy, Immunoelectron Paraproteinemias / complications* |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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