| Immunosuppressive medications during pregnancy and lactation in women with autoimmune diseases. | |
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MedLine Citation:
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PMID: 20426608 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Most autoimmune diseases predominantly affect females. Many of these diseases occur in women who have the potential to become pregnant or wish to plan a pregnancy. The potential for fetotoxic effects of immunosuppressive medications that are commonly used to treat systemic autoimmune diseases must be weighed against the need for control of disease activity during pregnancy and the postpartum period, since active disease can be an independent risk factor for adverse pregnancy outcomes. Although far from conclusive, most data concerning the safety of medications for use during pregnancy come from case series and observational studies. It is often necessary to continue treating patients throughout pregnancy and lactation in order to control the activity of the underlying disease. The aim of this paper is to review the evidence regarding the safety of the most commonly used medications in rheumatic disease during pregnancy or lactation and to enable practitioners and patients to make informed decisions regarding treatment during this period in a woman's life. |
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Authors:
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Amy B Elliott; Eliza F Chakravarty |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Women's health (London, England) Volume: 6 ISSN: 1745-5065 ISO Abbreviation: Womens Health (Lond Engl) Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-04-29 Completed Date: 2010-06-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101271249 Medline TA: Womens Health (Lond Engl) Country: England |
Other Details:
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Languages: eng Pagination: 431-40; quiz 441-2 Citation Subset: IM |
Affiliation:
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Division of Immunology & Rheumatology, Stanford University School of Medicine, Palo Alto, CA 94304, USA. amy_b_elliott@yahoo.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antirheumatic Agents
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adverse effects,
therapeutic use* Autoimmune Diseases / drug therapy Breast Feeding Female Humans Immunosuppressive Agents / adverse effects*, therapeutic use Lactation / drug effects* Pregnancy Pregnancy Complications / drug therapy* Pregnancy Outcome Rheumatic Diseases / complications, drug therapy* |
| Chemical | |
Reg. No./Substance:
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0/Antirheumatic Agents; 0/Immunosuppressive Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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