| Immunosuppression for myelodysplastic syndrome: how bench to bedside to bench research led to success. | |
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MedLine Citation:
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PMID: 20359629 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Laboratory evidence and clinical evidence suggest that some patients with myelodysplastic syndrome (MDS) have immunologically mediated disease. This article describes the laboratory evidence supporting a role for the immune system in the marrow failure of MDS and clinical trials using IST in these patients. |
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Authors:
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Elaine M Sloand; A J Barrett |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Hematology/oncology clinics of North America Volume: 24 ISSN: 1558-1977 ISO Abbreviation: Hematol. Oncol. Clin. North Am. Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-04-02 Completed Date: 2010-06-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8709473 Medline TA: Hematol Oncol Clin North Am Country: United States |
Other Details:
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Languages: eng Pagination: 331-41 Citation Subset: IM |
Copyright Information:
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Published by Elsevier Inc. |
Affiliation:
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Hematology Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, 10 Center Drive, Bethesda, MD 20892, USA. sloande@nhlbi.nih.gov |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Antilymphocyte Serum / therapeutic use Apoptosis Biomedical Research Bone Marrow / pathology Clinical Medicine Clinical Trials as Topic / statistics & numerical data Cyclosporine / therapeutic use Cytokines / secretion Female Humans Immunosuppression* Immunosuppressive Agents / therapeutic use* Male Middle Aged Myelodysplastic Syndromes / drug therapy*, immunology, pathology T-Lymphocytes / immunology Tumor Necrosis Factor-alpha / antagonists & inhibitors, physiology |
| Chemical | |
Reg. No./Substance:
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0/Antilymphocyte Serum; 0/Cytokines; 0/Immunosuppressive Agents; 0/Tumor Necrosis Factor-alpha; 59865-13-3/Cyclosporine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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