Document Detail


Immunoreactive met-enkephalin plasma concentrations in chronic alcoholics and in children born from alcoholic mothers.
MedLine Citation:
PMID:  6633159     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Several experimental and clinical observations indicate that ethanol ingestion induces specific neurochemical modifications in the Central Nervous System. In particular, an involvement of endogenous opiates has been suggested in the case of alcohol addiction. In this light, the plasma concentrations of met-enkephalin immunoreactive peptides (ME-IR) have been measured in selected groups of chronic alcoholics and in children whose mothers were ethanol addicts. Both groups revealed a marked reduction of ME-IR plasma concentrations when compared with sex and age matched controls.
Authors:
S Govoni; A Bosio; E Di Monda; G Fazzari; P F Spano; M Trabucchi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Life sciences     Volume:  33     ISSN:  0024-3205     ISO Abbreviation:  Life Sci.     Publication Date:  1983 Oct 
Date Detail:
Created Date:  1983-12-17     Completed Date:  1983-12-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0375521     Medline TA:  Life Sci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1581-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Alcoholism / blood*
Child
Child, Preschool
Enkephalin, Methionine / blood*
Female
Humans
Male
Pregnancy
Prenatal Exposure Delayed Effects*
Chemical
Reg. No./Substance:
58569-55-4/Enkephalin, Methionine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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