Document Detail

Immunoperoxidase confirmation of parathyroid origin of ultrasound-guided fine needle aspirates of the parathyroid glands.
MedLine Citation:
PMID:  3544627     Owner:  NLM     Status:  MEDLINE    
It may be difficult to differentiate between cells of parathyroid and thyroid origin in ultrasound-guided fine needle aspirations of the neck region, even in patients with a clinical history of hyperparathyroidism. A parathyroid hormone antibody was used in an immunohistochemical system to confirm a parathyroid origin in fine needle aspirate smears from nine patients with hyperparathyroidism. Immunoperoxidase positivity for parathyroid hormone confirmed a parathyroid origin in six of nine cases and was strongly suggestive, although equivocal, in the remaining three cases. Technical problems included nonuniform staining and background staining.
B Winkler; G A Gooding; C K Montgomery; O H Clark; C Arnaud
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Acta cytologica     Volume:  31     ISSN:  0001-5547     ISO Abbreviation:  Acta Cytol.     Publication Date:    1987 Jan-Feb
Date Detail:
Created Date:  1987-03-17     Completed Date:  1987-03-17     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370307     Medline TA:  Acta Cytol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  40-4     Citation Subset:  IM    
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MeSH Terms
Adenoma / pathology
Biopsy, Needle / methods
Hyperparathyroidism / diagnosis*,  pathology
Immunoenzyme Techniques
Parathyroid Diseases / diagnosis*,  pathology
Parathyroid Hormone / analysis
Grant Support
Reg. No./Substance:
0/Parathyroid Hormone

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